推薦產品
化驗
≥98% (HPLC)
形狀
powder
溶解度
methanol: 1 mg/mL, clear, very light yellow
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
COc1c(O)cc2Oc3cc(O)c(C\C=C(\C)C)c(O)c3C(=O)c2c1C\C=C(/C)C
InChI
1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3
InChI 密鑰
GNRIZKKCNOBBMO-UHFFFAOYSA-N
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一般說明
α-倒捻子素(α-MG)是丰富的植物化学成分,可从山竹获得。它是四氧二异戊烯化氧杂蒽酮。α-MG分子的化学结构为1,3,6-三羟-7-甲氧基-2,8-双(3-甲基-2-丁烯基)- 9H-氧杂蒽-9-酮。
應用
α-倒捻子素已被用于:
- 研究对氧化应激介导的视网膜细胞死亡的保护作用
- 研究其作为抗遗传毒性试剂在DNA氧化损伤保护中的作用
- 了解其抵御表皮葡萄球菌 RP62A的抗菌活性
生化/生理作用
α-倒捻子素在体外和体内研究中均展现出各种药理性质。 这些特性包括抗菌、抗癌、抗糖尿病、神经保护、护肝和抗炎。
从山竹( 山竹 )中分离得到的黄酮类衍生物。抗氧化和抗炎。
从山竹( 山竹 )中分离得到的黄酮类衍生物。抗氧化和抗炎。研究表明,α-山竹素通过线粒体途径诱导细胞凋亡,减少细胞增殖,抑制肿瘤的发生。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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There is a need to characterize promising dietary agents for chemoprevention and therapy of prostate cancer (PCa). We examined the anticancer effect of α-mangostin, derived from the mangosteen fruit, in human PCa cells and its role in targeting cell cycle-related
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PloS one, 7(3), e33376-e33376 (2012-03-20)
α-Mangostin, isolated from the hulls of Garcinia mangostana L., was found to have in vitro cytotoxicity against 3T3-L1 cells as well as inhibiting fatty acid synthase (FAS, EC 2.3.1.85). Our studies showed that the cytotoxicity of α-mangostin with IC(50) value
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Fabiola Gutierrez-Orozco et al.
Journal of agricultural and food chemistry, 61(16), 3891-3900 (2013-04-13)
Information about the anti-inflammatory activity and metabolism of α-mangostin (α-MG), the most abundant xanthone in mangosteen fruit, in human cells is limited. On the basis of available literature, we hypothesized that α-MG will inhibit the secretion of pro-inflammatory mediators by
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