跳轉至內容
Merck
全部照片(4)

重要文件

M3824

Sigma-Aldrich

α1,3,6-三羟基-7-甲氧基-2,8-双(3-甲基-2-丁烯基)-9H-氧杂蒽-9-酮

≥98% (HPLC)

同義詞:

α-MG, alpha-Mangostin

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C24H26O6
CAS號碼:
分子量::
410.46
EC號碼:
MDL號碼:
分類程式碼代碼:
12352212
PubChem物質ID:
NACRES:
NA.25

化驗

≥98% (HPLC)

形狀

powder

溶解度

methanol: 1 mg/mL, clear, very light yellow

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

SMILES 字串

COc1c(O)cc2Oc3cc(O)c(C\C=C(\C)C)c(O)c3C(=O)c2c1C\C=C(/C)C

InChI

1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3

InChI 密鑰

GNRIZKKCNOBBMO-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

α-倒捻子素(α-MG)是丰富的植物化学成分,可从山竹获得。它是四氧二异戊烯化氧杂蒽酮。α-MG分子的化学结构为1,3,6-三羟-7-甲氧基-2,8-双(3-甲基-2-丁烯基)- 9H-氧杂蒽-9-酮。

應用

α-倒捻子素已被用于:
  • 研究对氧化应激介导的视网膜细胞死亡的保护作用
  • 研究其作为抗遗传毒性试剂在DNA氧化损伤保护中的作用
  • 了解其抵御表皮葡萄球菌 RP62A的抗菌活性

生化/生理作用

α-倒捻子素在体外和体内研究中均展现出各种药理性质。 这些特性包括抗菌、抗癌、抗糖尿病、神经保护、护肝和抗炎。
从山竹( 山竹 )中分离得到的黄酮类衍生物。抗氧化和抗炎。
从山竹( 山竹 )中分离得到的黄酮类衍生物。抗氧化和抗炎。研究表明,α-山竹素通过线粒体途径诱导细胞凋亡,减少细胞增殖,抑制肿瘤的发生。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

客戶也查看了

Ali Ghasemzadeh et al.
Molecules (Basel, Switzerland), 23(8) (2018-07-26)
Since α-mangostin in mangosteen fruits was reported to be the main compound able to provide natural antioxidants, the microwave-assisted extraction process to obtain high-quality α-mangostin from mangosteen pericarp (Garcinia mangostana L.) was optimized using a central composite design and response
Jeremy J Johnson et al.
Carcinogenesis, 33(2), 413-419 (2011-12-14)
There is a need to characterize promising dietary agents for chemoprevention and therapy of prostate cancer (PCa). We examined the anticancer effect of α-mangostin, derived from the mangosteen fruit, in human PCa cells and its role in targeting cell cycle-related
Xiaofang Quan et al.
PloS one, 7(3), e33376-e33376 (2012-03-20)
α-Mangostin, isolated from the hulls of Garcinia mangostana L., was found to have in vitro cytotoxicity against 3T3-L1 cells as well as inhibiting fatty acid synthase (FAS, EC 2.3.1.85). Our studies showed that the cytotoxicity of α-mangostin with IC(50) value
DNA Protection against Oxidative Damage Using the Hydroalcoholic Extract of Garcinia mangostana and Alpha-Mangostin.
Carvalho-Silva R
Evidence-Based Complementary and Alternative Medicine : ECAM, 2016, 3430405-3430405 (2016)
Fabiola Gutierrez-Orozco et al.
Journal of agricultural and food chemistry, 61(16), 3891-3900 (2013-04-13)
Information about the anti-inflammatory activity and metabolism of α-mangostin (α-MG), the most abundant xanthone in mangosteen fruit, in human cells is limited. On the basis of available literature, we hypothesized that α-MG will inhibit the secretion of pro-inflammatory mediators by

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務