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Merck
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重要文件

M3379

Sigma-Aldrich

DL-Methioninol

≥95%

同義詞:

4-Methylmercapto-2-amino-1-butanol

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About This Item

經驗公式(希爾表示法):
C5H13NOS
CAS號碼:
分子量::
135.23
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.26

產品名稱

DL-Methioninol, ≥95%, viscous liquid

化驗

≥95%

形狀

viscous liquid

顏色

colorless to faint yellow

應用

cell analysis

SMILES 字串

CSCCC(N)CO

InChI

1S/C5H13NOS/c1-8-3-2-5(6)4-7/h5,7H,2-4,6H2,1H3

InChI 密鑰

MIQJGZAEWQQAPN-UHFFFAOYSA-N

生化/生理作用

Methioninol is a methionine derivative that has been shown to inhibit SDK and TREK-1 channels in COS cells.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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S A Baker et al.
British journal of pharmacology, 153(6), 1259-1271 (2008-01-22)
During the bladder filling phase, the volume of the urinary bladder increases dramatically, with only minimal increases in intravesical pressure. To accomplish this, the smooth muscle of the bladder wall must remain relaxed during bladder filling. However, the mechanisms responsible
Methionine and its derivatives increase bladder excitability by inhibiting stretch-dependent K+ channels.
Baker, S.A. et al.
British Journal of Pharmacology, 53, 1259-1271 (2008)
Homar S Barcena et al.
Organic letters, 5(5), 709-711 (2003-02-28)
One-electron reduction inverts the helicity of copper complexes formed from derivatives of S-methylcysteine and methioninol. The change in conformation of the organic ligand is followed in the exciton-coupled circular dichroism (ECCD) spectra of the complexes.

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