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L9879

Sigma-Aldrich

番茄红素

≥90%, from tomato

同義詞:

ψ,ψ-胡萝卜素, 2,6,10,14,19,23,27,31-八甲基-三十二烷-2,6,8,10,12,14,16,18,20,22,24,26,30-十三烯

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About This Item

經驗公式(希爾表示法):
C40H56
CAS號碼:
分子量::
536.87
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

生物源

tomato

化驗

≥90%

形狀

powder

運輸包裝

dry ice

儲存溫度

−70°C

SMILES 字串

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

InChI 密鑰

OAIJSZIZWZSQBC-GYZMGTAESA-N

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一般說明

番茄红素是一种天然产生的红色素,属于类胡萝卜素家族成员。它存在于番茄、西瓜和木瓜中。番茄红素具有抗氧化性。

應用

番茄红素已用于:
  • 通过高效液相色谱(HPLC)测定其在肝、肾和肺组织中的浓度
  • 激活前列腺癌细胞系中的尿激酶型纤溶酶原激活物受体(uPAR)
  • 在拉曼光谱成像中检测和可视化其内分布。

生化/生理作用

西红柿中的抗氧化剂微量营养素,与降低癌症和心血管疾病风险有关。通过间隙连接蛋白 43 的表达上调促进细胞间间隙连接通讯以及抑制培养中癌细胞增殖。抑制胆固醇合成以及促进低密度脂蛋白降解。

包裝

密封安瓿瓶装

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Chun-Ming Shih et al.
Polymers, 12(7) (2020-07-15)
Lycopene is the most abundant carotenoid in tomatoes, which has been identified to have the properties of anti-inflammation in addition to the capability to inhibit the expression of adhesion molecules. Intercellular adhesion molecules play a critical role in the pathogenesis
Harris H Wang et al.
Nature, 460(7257), 894-898 (2009-07-28)
The breadth of genomic diversity found among organisms in nature allows populations to adapt to diverse environments. However, genomic diversity is difficult to generate in the laboratory and new phenotypes do not easily arise on practical timescales. Although in vitro
Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication
Forbes K, et al.
Exp. Biol. Med, 228(8), 967-971 (2003)
Arnab Chattopadhyay et al.
Journal of lipid research, 54(4), 995-1010 (2013-02-05)
Transgenic tomato plants were constructed with an empty vector (EV) or a vector expressing an apoA-I mimetic peptide, 6F. EV or 6F tomatoes were harvested, lyophilized, ground into powder, added to Western diet (WD) at 2.2% by weight, and fed
Investigation of Raman chemical imaging for detection of lycopene changes in tomatoes during postharvest ripening
Qin J, et al.
Journal of Food Engineering, 107(3-4), 277-288 (2011)

文章

肝脏中胆固醇的合成量由饮食中的胆固醇水平来严格调节。LDL受体调节富含脂质的低密度脂蛋白(LDL)颗粒的细胞转运。

Cholesterol synthesis regulation by dietary levels, LDL receptors control lipid-rich LDL particle transport in cells.

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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