暫時無法取得訂價和供貨情況
推薦產品
生物源
Larix kaempferi
化驗
≥98% (HPLC)
形狀
powder or crystals
儲存條件
protect from light
顏色
white to off-white
溶解度
methanol: 1 mg/mL, clear, colorless
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
O=C(OC)C1=CC[C@@]2(C(O[C@@](/C=C/C=C(C(O)=O)\C)(C)[C@@H]3CC2)=O)[C@]3(OC(C)=O)CC1
InChI
1S/C23H28O8/c1-14(17(24)25)6-5-10-21(2)16-9-12-22(19(27)31-21)11-7-15(18(26)29-3)8-13-23(16,22)20(28)30-4/h5-7,10,16H,8-9,11-13H2,1-4H3,(H,24,25)/b10-5+,14-6+/t16-,21+,22+,23+/m0/s1
InChI 密鑰
XRLYZNSOXNPKOR-CBDALDGHSA-N
尋找類似的產品？ 前往 產品比較指南
生化／生理作用
土槿皮中分离得到天然二萜类化合物土槿皮乙酸B。它已显示出抗真菌，抗生育和抗血管生成特性。它还可能具有抗癌和抗炎特性。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Repr. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ai-guo Meng et al.
Acta pharmacologica Sinica, 30(4), 442-450 (2009-03-24)
The aim of this study was to investigate the mechanism of pseudolaric acid B (PLAB)-induced cell cycle arrest in human melanoma SK-28 cells. Cell growth inhibition was detected by MTT assay, the cell cycle was analyzed by flow cytometry, and
Taradas Sarkar et al.
Biochemical pharmacology, 84(4), 444-450 (2012-05-29)
We purified pseudolaric acid B (PAB) from the root and stem bark of Pseudolarix kaempferi (Lindl.) Gorden. Confirming previous findings, we found that the compound had high nanomolar IC₅₀ antiproliferative effects in several cultured cell lines, causing mitotic arrest and
Min Qi et al.
Journal of pharmacological sciences, 121(3), 200-211 (2013-02-27)
Pseudolaric acid B (PAB) is the primary biologically active compound isolated from the root bark of P. kaempferi Gordon. Our previous study demonstrated that PAB induced mitotic catastrophe in L929 cells and indicated that only a small percentage (12%) of
Barry M Trost et al.
Journal of the American Chemical Society, 130(48), 16424-16434 (2008-11-13)
We report a full account of our work toward the total synthesis of pseudolaric acid B (1a), a diterpene acid isolated from the bark of Pseudolarix kaempferi Gordon (pinaceae). Compound 1a is an antifungal and antifertility agent. Furthermore, its capacity
Ze-hong Miao et al.
Acta pharmacologica Sinica, 33(9), 1103-1111 (2012-08-28)
In the past decade, the success of angiogenesis inhibitors in clinical contexts has established the antiangiogenic strategy as an important part of cancer therapy. During that time period, we have discovered and reported 17 compounds that exert potent inhibition on
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