推薦產品
生物源
human
品質等級
重組細胞
expressed in E. coli
化驗
>97% (SDS-PAGE)
形狀
lyophilized powder
效力
0.2-4.0 ng/mL EC50
分子量
antigen predicted mol wt ~12.5 kDa
包裝
pkg of 5 μg
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
UniProt登錄號
儲存溫度
−20°C
基因資訊
human ... IL15(3600)
相關類別
生化／生理作用
IL-15（白介素15）是一种多效促炎性细胞因子，是先天性和适应性免疫反应之间的连接纽带。它参与各种淋巴细胞谱系的增殖、存活和激活。 IL-15 的作用是与含有IL-15Rα、IL-2/15Rβ 和 IL-Rγ的高亲和力异源三聚体受体复合物结合。和IL-R＆＃947;。它以不同的形式存在，如由 IL-15 受体α 链和可溶的细胞因子结合形成的可溶 Hhyper Il-15，以及膜结合亚型。
白介素-15最先从猴肾脏上皮细胞系的培养上清液中分离取得。 它的cDNA编码162个氨基酸的前体蛋白，其中带有48个氨基酸的信号肽，切除后生成114个氨基酸的成熟蛋白。人IL-15与猴(~97%)和鼠(~73%)IL-15具有序列一致性。IL-15会与IL-2竞争结合位点，因两者均通过IL-2受体刺激细胞生长。
外觀
从 pH 7.4 的磷酸盐缓冲盐水中 0.2 µm 过滤溶液冻干所得，每 1 μg 中含 50 μg 牛血清白蛋白作为载体蛋白。
分析報告
使用 Mo7e 人巨核细胞白血病细胞，通过细胞增殖检测进行测定。人重组 IL-15 的比活性约为 4.5 x 105 U/μg——此数值已针对人重组 IL-15 WHO 国际标准（NIBSC 代码：95/554）进行了校准。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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文章
Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
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