This product is offered in a powdered format. Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.
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About This Item
經驗公式（希爾表示法）:
C14H16N4
CAS號碼:
分子量：:
240.30
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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產品名稱
咪喹莫特, ≥98% (HPLC), solid
品質等級
化驗
≥98% (HPLC)
形狀
solid
溶解度
H2O: <2 mg/mL
DMSO: 4 mg/mL (warming to 60 °C for 15 minutes)
SMILES 字串
CC(C)Cn1cnc2c(N)nc3ccccc3c12
InChI
1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
InChI 密鑰
DOUYETYNHWVLEO-UHFFFAOYSA-N
基因資訊
human ... TLR7(51284)
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一般說明
Imiquimod is a toll-like receptor (TLR)-7/8 agonist.[1]
應用
生化／生理作用
咪喹莫特是半胱天冬酶 3 激活剂，可直接诱导半胱天冬酶 3 裂解为活性半胱天冬酶 3。咪喹莫特在体内 诱导基底细胞癌凋亡 。其抗肿瘤活性与诱导细胞凋亡有关。咪喹莫特具有抗血管生成、抗炎、抗病毒活性。咪喹莫特还可作为免疫应答调节剂，诱导多种细胞因子和趋化因子的分泌。
咪喹莫特是半胱天冬酶 3 激活剂，可直接诱导半胱天冬酶 3 裂解为活性半胱天冬酶 3。咪喹莫特在体内可诱导细胞凋亡 ，并作为一种免疫调节剂，具有抗病毒和抗炎特性。
Imiquimod helps to induce the innate cutaneous immunity and the cellular arm of the adaptive immune response.[1]
特點和優勢
This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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分析證明 (COA)
Lot/Batch Number
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