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Merck
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重要文件

HPA023371

Sigma-Aldrich

Anti-DCXR antibody produced in rabbit

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1

同義詞:

Anti-Carbonyl reductase II, Anti-Dicarbonyl/L-xylulose reductase, Anti-Kidney dicarbonyl reductase, Anti-L-xylulose reductase, Anti-Sperm surface protein P34H, Anti-XR, Anti-kiDCR

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About This Item

分類程式碼代碼:
12352203
人類蛋白質圖譜編號:
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

產品線

Prestige Antibodies® Powered by Atlas Antibodies

形狀

buffered aqueous glycerol solution

物種活性

human

加強驗證

orthogonal RNAseq
Learn more about Antibody Enhanced Validation

技術

immunoblotting: 0.04-0.4 μg/mL
immunohistochemistry: 1:500-1:1000

免疫原序列

IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEG

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... DCXR(51181)

一般說明

Dicarbonyl/L-xylulose reductase, kidney dicarbonyl reductase, sperm surface protein P34H (DCXR, DCR) is an uronate cycle of glucose metabolism NADPH-linked reductase that catalyzes α-dicarbonyl and l-xylulose. DCXR is highly expressed in kidney proximal renal tubule inner membranes. DCXR/P34H is also found on the acrosomal cap of epididymal sperm and is considered to be a marker of sperm maturation.
Rabbit polyclonal DCXR antibody reacts with human dicarbonyl/L-xylulose reductase, kidney dicarbonyl reductase, sperm surface protein P34H.

免疫原

L-xylulose reductase recombinant protein epitope signature tag (PrEST)

應用

Rabbit polyclonal DCXR antibody is used to tag dicarbonyl/L-xylulose reductase for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of dicarbonyl/L-xylulose reductase in uronate cycle metabolism, and kidney and sperm function.

特點和優勢

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

聯結

Corresponding Antigen APREST75801

外觀

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

法律資訊

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ann F Hubbs et al.
The American journal of pathology, 181(3), 829-844 (2012-08-17)
Flavorings-related lung disease is a potentially disabling disease of food industry workers associated with exposure to the α-diketone butter flavoring, diacetyl (2,3-butanedione). To investigate the hypothesis that another α-diketone flavoring, 2,3-pentanedione, would cause airway damage, rats that inhaled air, 2,3-pentanedione

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