H8909

HBcAg 核心 人

~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli

• 同義詞: Hepatitis B virus core antigen
• MDL號碼: MFCD02264925
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 重組細胞: expressed in E. coli
• 品質等級: 200
• 化驗: ≥95% (SDS-PAGE)
• 分子量: 18 kDa
• 濃度: ~1 mg/mL
• UniProt登錄號: G9G988
• 儲存溫度: −20°C
• 基因資訊: hepatitis B virus ... HBVgp4(944568) ; human ... HBVgp4(944568)

描述

一般說明

amino acids 1-183 of HBV core antigen.

生化／生理作用

HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication.

Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg). The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels. High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation.

外觀

Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable