推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen ~50 kDa
物種活性
human
濃度
~1.0 mg/mL
技術
western blot: 1-2 μg/mL using lysates of HEK-293T cells over expressing human HOXA10
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... HOXA10(3206)
一般說明
The homeobox A10 (HOXA10) protein is localized in the adult human endometrium. The HOXA10 gene is mapped on the human chromosome at 7p15.2.
特異性
Anti-HOXA10 (N-terminal) recognizes human HOXA10 (also known as Hox-1H and HOX-1).
應用
Anti-HOXA10 (N-terminal) antibody produced in rabbit has been used in immunoblotting.
生化／生理作用
Homeobox A10 (HOXA10) protein is critical for the normal development of the erythroid and megakaryocytic lineages. The expression of the HOXA10 gene was found to be altered in endometriosis. HOXA10 protein plays a role in mediating endometrial development during the menstrual cycle. This protein is also involved in preparing the endometrium for implantation in humans.
外觀
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
儲存和穩定性
For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Alysson Zanatta et al.
Journal of assisted reproduction and genetics, 27(12), 701-710 (2010-09-08)
endometriosis and its associated infertility have been the object of continuous research for over a century. To understand the molecular mechanisms underlying the disease, it has become necessary to determine the aspects of its etiology that are not explained by
J Julie Kim et al.
Molecular human reproduction, 13(5), 323-332 (2007-03-14)
Endometriosis is a poorly understood gynaecologic disorder that is associated with infertility. In this study, we examined the expression of HOXA10 in the eutopic endometrium of baboons with induced endometriosis. A decrease in HOXA10 mRNA was observed after 3, 6
H S Taylor et al.
The Journal of clinical investigation, 101(7), 1379-1384 (1998-04-29)
Hox genes are well-known transcriptional regulators that play an essential role in directing embryonic development. Mice that are homozygous for a targeted disruption of the Hoxa10 gene exhibit uterine factor infertility. We have recently demonstrated that HOXA10 is expressed in
Nan Zhu et al.
The Journal of clinical investigation, 126(3), 997-1011 (2016-02-16)
Self-renewal is a hallmark of both hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs); therefore, the identification of mechanisms that are required for LSC, but not HSC, function could provide therapeutic opportunities that are more effective and less toxic
Edward J Richards et al.
Oncotarget, 6(33), 34745-34757 (2015-10-03)
The homeobox A (HOXA) region of protein-coding genes impacts female reproductive system embryogenesis and ovarian carcinogenesis. The 5-prime end of HOXA includes three long non-coding RNAs (lncRNAs) (HOXA10-AS, HOXA11-AS, and HOTTIP) that are underexplored in epithelial ovarian cancer (EOC). We
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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