推薦產品
生物源
chicken
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
製造商／商標名
Genway 15-288-10072F
技術
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CRP(1401)
一般說明
C-reactive protein (CRP) is a member of a protein family that serve as soluble pattern recognition molecules. This protein is generated and liberated in the circulation in response to infection and tissue damage. CRP gene is located on human chromosome 1q23.2.
CRP is synthesized by human peripheral blood mononuclear cells. The CRP gene is localized to chromosome 1.
應用
Anti-C-Reactive Protein antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. It is also suitable for indirect ELISA.
生化／生理作用
C-Reactive Protein (CRP) is a homopentamer that belongs to the pentaxin family. CRP binds to phosphorylcholine in a calcium dependent manner and plays a key role in host defense. It is involved in several defense mechanisms such as, agglutination, bacterial capsular swelling, phagocytosis and complement fixation. CRP interacts with secreted M-ficolin anchored to monocyte transmembrane G protein-coupled receptor 43 and mediates immune signaling and regulates host defense. It scavenges nuclear waste that is released from cells following apoptosis.
C-reactive protein (CRP) plays a major role the early stages of atherosclerosis and pantothenic acid (PA). It shows an antioxidant effect in inflammatory process. The active monomeric form of C-reactive protein (CRP) is involved in proinflammatory functions.
外觀
Solution in phosphate buffered saline containing 0.02% sodium azide.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
The long-term relationship between dietary pantothenic acid (vitamin B5) intake and C-reactive protein concentration in adults aged 40 years and older.
Jung S, et al.
Nutrition, Metabolism, and Cardiovascular Diseases, 27(9), 806-816 (2017)
T M Murphy et al.
The Journal of experimental medicine, 173(2), 495-498 (1991-02-01)
We synthesized and cloned cDNA from human peripheral blood mononuclear cell (PBMC) transcripts that were hybrid selected by pCRP5, a liver C-reactive protein (CRP)-specific cDNA (Woo, P.,J.R. Korenberg, and A.S. Whitehead. 1985. J.Biol. Chem. 260:13384). Three hybrid-selected cDNA clones, HScDNA1
An intrinsically disordered motif mediates diverse actions of monomeric C-reactive protein.
Li HY, et al.
The Journal of Biological Chemistry, 291(16), 8795-8804 (2016)
S Danese et al.
Alimentary pharmacology & therapeutics, 34(1), 1-10 (2011-05-05)
The addition of antitumour necrosis factor-α (TNF-α) agents to the therapeutic armamentarium against Crohn's disease has been a revolution in its management. However, approximately 25 to 40% of patients who initially benefit from anti-TNF-α treatment develop intolerable adverse events or
A P Osmand et al.
Proceedings of the National Academy of Sciences of the United States of America, 74(2), 739-743 (1977-02-01)
Partial amino acid sequences of rabbit C-reactive protein, a peptide derived from human C-reactive protein by cyanogen bromide cleavage, and the C1t subcomponent of the human complement component C1 have been determined. Extensive sequence homology between these proteins establish their
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