G9880

谷丙转氨酶 来源于猪心脏

ammonium sulfate suspension, ≥75 units/mg protein

• 同義詞: L-丙氨酸:2-酮戊二酸氨基转移酶, GPT, 丙氨酸氨基转移酶（催化浓度）
• CAS號碼: 9000-86-6
• 酶委員會編號: 2.6.1.2 (BRENDA, IUBMB)
• Beilstein: 3562140
• EC號碼: 232-561-4
• MDL號碼: MFCD00131192
• 分類程式碼代碼: 12352204
• NACRES: NA.54

屬性

• 生物源: Porcine heart
• 形狀: ammonium sulfate suspension
• 比活性: ≥75 units/mg protein
• 分子量: 42 kDa
• 異物活動: L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%; glutamic-oxalacetic transaminase ≤0.05%
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C

描述

一般說明

Research area: Cell Signaling
Glutamic-pyruvic transaminase (GPT) is located in most cells in the body but is found in highest concentrations in the liver. Two GPT isoforms, GPT1 and GPT2, are present in mammals.

應用

Glutamic-Pyruvic Transaminase from porcine heart has been used to determine L-lactate levels in aqueous polyethylene glycol (PEG) solutions.

生化／生理作用

GPT is responsible for catalyzing the reversible transamination of α-ketoglutarate and alanine to glutamate and pyruvate. It also plays a critical role in the metabolism of amino acids and gluconeogenesis.

谷丙转氨酶 (GPT) 存在于体内大多数细胞中，但在肝脏中浓度最高。由于在肝细胞坏死后 GPT 释放入血液，可作为肝脏疾病的标志物。

單位定義

一个单位在37℃和pH 7.6，L-丙氨酸存在条件下将1.0μmole α酮戊二酸转化成L-谷氨酸。

外觀

1.8M (NH₄)₂SO₄ 溶液中的悬浮液，pH 6.0

分析報告

由缩二脲确定的蛋白质。

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H334
• 防範說明: P261 - P284 - P501
• 危險分類: Resp. Sens. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)