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G9270

Sigma-Aldrich

γ-谷氨酰转肽酶 来源于马肾脏

Type VI, 5-12 units/mg solid

同義詞:

γ-谷氨酰转移酶, γ;-GT, GGTP, (5-谷氨酰)肽:氨基酸 5-谷氨酰转移酶

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About This Item

CAS號碼:
酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54
暫時無法取得訂價和供貨情況

生物源

equine kidney

品質等級

種類

Type VI

形狀

solid

比活性

5-12 units/mg solid

儲存溫度

−20°C

一般說明

γ-谷氨酰转肽酶是一种异二聚酶[1],属于N端亲核水解酶超家族。[2]

應用

来自马肾的γ-谷氨酰转肽酶已用于:

  • 鉴定河豚肝脏中4-S-半胱氨酸河豚毒素的形成[3]
  • 作为标准品,用于测定人B细胞淋巴瘤细胞裂解物的γ -谷氨酰转移酶的活性[4]
  • 解异肽,以研究其对微管蛋白聚集的影响[5]

生化/生理作用

γ-谷氨酰转肽酶参与谷胱甘肽代谢,可以催化γ -谷氨酰化合物的裂解,如谷胱甘肽。它还对γ -谷氨酰基向氨基酸和多肽的转移发挥着作用。[1]

品質

粗品

單位定義

在 25°C、pH 8.5 的条件下,一个单位每分钟从 L-γ-谷氨酰-β-硝基苯胺中释放出 1.0 μmol 对硝基苯胺。

抑制劑

產品號碼
描述
訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Gina Boanca et al.
The Journal of biological chemistry, 281(28), 19029-19037 (2006-05-05)
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The metabolic pathway of tetrodotoxin (TTX), a powerful and specific voltage-gated sodium channel blocker, has not been well-clarified either in TTX-poisoned patients or in puffer fish. 4-S-CysteinylTTX (4-CysTTX) was isolated from the liver of the puffer fish, Fugu pardalis, as
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The aim of this study was to characterize three new, recently established non-Hodgkin lymphoma cell lines (GUMBUS, DOGUM, and DOGKIT), isolated from patients developing high-clinical resistance to cytotoxic therapy, with respect to sensitivity toward 21 antitumor drugs from different classes
H Suzuki et al.
Amino acids, 32(3), 333-340 (2006-10-13)
Some amino acids and peptides, which have low solubility in water, become much more soluble following gamma-glutamylation. Compounds become more stable in the blood stream with gamma-glutamylation. Several gamma-glutamyl compounds are known to have favorable physiological effects on mammals. Gamma-glutamylation

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