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FD40S

Sigma-Aldrich

异硫氰酸荧光素-葡聚糖

average mol wt 40,000

同義詞:

FITC-右旋糖酐

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About This Item

CAS號碼:
60842-46-8
MDL號碼:
MFCD00131092
分類程式碼代碼:
12352201
NACRES:
NA.25
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生物源

synthetic (organic)

共軛

FITC conjugate

形狀

powder

分子量

average mol wt 40,000

標籤範圍

0.003-0.020 mol FITC per mol glucose

顏色

yellow to dark orange

溶解度

H2O: soluble 25 mg/mL, clear to slightly hazy, yellow to deep orange

儲存溫度

2-8°C

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相關類別

一般說明

葡聚糖是葡萄糖酐聚合物。由大约95%的α-D-(166)键组成。剩余的（163）键作为葡聚糖的分支。[1][2] 天然葡聚糖的分子量(MW)经证实在 900 万至 5 亿的范围内。[3]FITC-葡聚糖的最大激发波长为 490nm。它的 pH 范围为 5 至 9。 [4]

應用

异硫氰酸荧光素-葡聚糖（FITC-右旋糖酐，荧光素右旋糖酐，FITC）用于以下过程：
  • 荧光素-葡聚糖显微镜。[5][6][7]
  • 评估多形核白细胞α防御素表达转基因小鼠体内肺血管的通透性。[8]
  • 通过流式细胞术定量细胞吞噬能力。[9]
  • 标记α乳白蛋白和脱氧核糖核酸酶。[10]
FITC-葡聚糖广泛用于运用显微荧光法进行微循环和细胞通透性研究。它还适用于植物细胞壁孔隙度和毛细血管通透性研究。
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。

聯結

与 FD-40 类似，但由 Sigma 生产。

準備報告

Sigma 通常以 25mg/ml 或更高的浓度测试 FITC 葡聚糖在水中的溶解度。 溶液应避光。 在体内，FITC-葡聚糖稳定超过 24 小时。

其他說明

为了全面了解我们针对客户研究提供的各种葡聚糖产品，建议您访问我们的碳水化合物分类页面。
天然葡聚糖的分子量(MW)经证实在 900 万至 5 亿的范围内。较低分子量的葡聚糖将表现出略微较少的分支，并且具有更窄的分子量分布范围。分子量大于 10,000 的葡聚糖则表现为高度支化。 随着分子量增加，葡聚糖分子的对称性增强。 分子量为 2,000 至 10,000 的葡聚糖表现出可膨胀线圈的特性。 在分子量低于 2,000 时，葡聚糖更像棒状。通过以下一种或多种方法测量葡聚糖的分子量：低角度激光散射、尺寸排阻色谱法、铜络合和蒽酮试剂显色还原末端糖测定和粘度。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
0000406281
0000385552
0000384637
0000341261
0000334014

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Kristina Krempaska et al.
Respiratory research, 21(1), 25-25 (2020-01-17)
Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease without a cure and new drug strategies are urgently needed. Differences in behavior between diseased and healthy cells are well known and drug response can be different between cells isolated
Molecular weight, molecular-weight distribution and molecular size of native dextran.
AROND L H and H P FRANK
The Journal of Physical Chemistry, 953 - 957 (1954)
Erika M J Siren et al.
Scientific reports, 8(1), 7581-7581 (2018-05-17)
Here we present a simple technique for re-directing reactions on the cell surface to the outermost region of the glycocalyx. Macromolecular crowding with inert polymers was utilized to reversibly alter the accessibility of glycocalyx proteoglycans toward cell-surface reactive probes allowing
Yun Mi Lee et al.
Journal of diabetes research, 2013, 245271-245271 (2013-12-29)
Retinal pathogenic angiogenesis in the eyes is a causative factor in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. This study was designed to examine the pathogenic role of the high-mobility group box-1 (HMGB1) protein and the inhibitory effect
Yun Mi Lee et al.
BMC complementary and alternative medicine, 15, 271-271 (2015-08-13)
Retinal neovascularization is a common cause of vision loss in proliferative diabetic retinopathy, retinopathy of prematurity and age-related macular degeneration. Samul-tang (SMT) is a widely used traditional herbal medicine in East Asia and is also known as Shimotsu-to in Japanese
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相關內容

Fluorescein Isothiocyanate-Dextran

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

異硫氰酸螢光素-葡聚糖

右旋糖酐是氫葡萄糖的聚合物。它由大約 95% 的 alpha-D-(166)連結組成。其餘的 (163) 連結構成了右旋糖酐的分支。

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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