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Merck
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文件

E8512

Sigma-Aldrich

Ethylmorphine

同義詞:

Morphine 3-ethyl ether

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About This Item

經驗公式（希爾表示法）:
C19H23NO3
CAS號碼:
76-58-4
分子量：:
313.39
EC號碼:
200-970-7
MDL號碼:
MFCD00083327
分類程式碼代碼:
12352200
PubChem物質ID:
24894676
NACRES:
NA.77

藥物控制

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
veterinary

儲存溫度

2-8°C

SMILES 字串

CCOc1ccc2C[C@@H]3C4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

InChI

1S/C19H23NO3/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18/h4-7,12-14,18,21H,3,8-10H2,1-2H3/t12-,13+,14-,18-,19-/m0/s1

InChI 密鑰

OGDVEMNWJVYAJL-LEPYJNQMSA-N

生化／生理作用

Narcotic analgesic; antitussive

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302,H336

防範說明

P301 + P312 + P330

危險分類

Acute Tox. 4 Oral - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

分析證明 (COA)

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Aliaa Nabil ElMeshad et al.
AAPS PharmSciTech, 21(7), 244-244 (2020-08-29)
Ethylmorphine hydrochloride (EtM) is a derivative of morphine used as analgesic to treat severe pain in case of cancer and bone injury. This study aimed to formulate and evaluate core in cup tablets containing 2 doses of EtM, the cup
Gyula Szucs et al.
Chemico-biological interactions, 147(2), 151-161 (2004-03-12)
Tiamulin, a diterpene antibiotic, is used for treatment of pulmonary and gastrointestinal infections in swine and poultry. Combined administration of tiamulin and ionophores (e.g. monensin) to farm animals may lead to intoxication manifested in severe clinical symptoms. Tiamulin metabolite complex
C Popa et al.
Journal of analytical toxicology, 22(2), 142-147 (1998-04-21)
In drugs-of-abuse testing, opiates constitute a delicate and controversial task because morphine may occur in urine for several reasons. Ethylmorphine (EtM), which is used as an antitussive drug in many countries, is metabolically converted to morphine. The present study was
K Hedenmalm et al.
Therapeutic drug monitoring, 19(6), 643-649 (1998-01-08)
The formation of morphine from codeine and ethylmorphine is mainly mediated by the polymorphic enzyme CYP2D6. The objective of this study was to investigate whether CYP2D6 poor metabolizers (PM) and CYP2D6 extensive metabolizers (EM) would respond differently during testing for
Ning Ding et al.
Bioorganic & medicinal chemistry letters, 21(12), 3531-3535 (2011-05-24)
Naphtho[2,1-α]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dione (NPCD) is known to be a very potent and selective cyclin D1-CDK4 inhibitors and could induce strong G1 phase arrest in breast tumor cell lines. In this work, the synthesis of five NPCD glycosides and their cytotoxic activities against
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