E1906

Anti-EAPII (TTRAP) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 同義詞: Anti-ETS1-associated Protein 2, Anti-TRAF and TNF Receptor Associated Protein
• MDL號碼: MFCD08705452
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~41 kDa by calculation
• 物種活性: human
• 技術: western blot: 1:1,000-1:5,000
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 基因資訊: human ... TTRAP(51567)

描述

免疫原

peptide corresponding to the human EAPII (amino acids 11-28).

應用

Anti-EAPII (TTRAP) antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:1000-1:5000.

生化／生理作用

Ets proteins are a family of conserved sequence specific DNA-binding proteins. They function as transcription factors with roles in differentiation, lymphoid cell development, invasiveness, and angiogenesis. ETS1-associated protein II (EAPII) interacts with ETS1 and other Ets proteins (ETS2 and FLI1). EAPII is mainly localized to the nucleus of mammalian cells. EAPII negatively modulates the transcriptional activity of ETS1. It reduces synergistic transactivation by ETS1 and AP-1. Re-expression of EAPII prevents the migration of epithelial cancer cells. It does not affect cell viability.

外觀

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable