D9069

N-Desmethyltamoxifen HCl

≥98% (HPLC), solid

• 同義詞: (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548
• 經驗公式（希爾表示法）: C₂₅H₂₇NO·HCl
• CAS號碼: 15917-65-4
• 分子量：: 393.95
• MDL號碼: MFCD03423594
• 分類程式碼代碼: 12352203
• PubChem物質ID: 329798889
• NACRES: NA.77

屬性

• 無菌: non-sterile
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• 技術: inhibition assay: suitable
• 溶解度: DMSO: ≥20 mg/mL
• 運輸包裝: ambient
• 儲存溫度: room temp
• SMILES 字串: Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3
• InChI: 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
• InChI 密鑰: GMLHJWZEYLTNJW-BJFQDICYSA-N

描述

應用

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

生化／生理作用

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

特點和優勢

This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H350,H360,H410
• 防範說明: P202 - P273 - P280 - P308 + P313 - P391 - P405
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges