推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white
溶解度
DMSO: 10 mg/mL, clear
H2O: insoluble
儲存溫度
2-8°C
SMILES 字串
COc1ccc(CCNC[C@H](O)c2ccc(O)cc2)cc1OC
InChI
1S/C18H23NO4/c1-22-17-8-3-13(11-18(17)23-2)9-10-19-12-16(21)14-4-6-15(20)7-5-14/h3-8,11,16,19-21H,9-10,12H2,1-2H3/t16-/m0/s1
InChI 密鑰
VHSBBVZJABQOSG-INIZCTEOSA-N
基因資訊
human ... ADRB1(153)
應用
R(-)-Denopamine has been used as an β-adrenergic agonist to study its effects on contractility in isolated lymphatic vessels (LVs).
生化／生理作用
Denopamine is a cardiotonic drug.
β1-adrenoceptor agonist.
特點和優勢
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
注意
光敏。
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
M Hirayama et al.
Rinsho shinkeigaku = Clinical neurology, 40(8), 787-790 (2001-02-24)
In 1993, we reported the pathophysiology of postprandial hypotension (PPH) in patients with sympathetic dysfunction: a fall of BP resulted from both excess systemic vasodilation and lack of compensatory increase of cardiac output and vascular resistance in the leg arteries.
Ruduwaan Salie et al.
Cardiovascular drugs and therapy, 25(1), 31-46 (2011-01-13)
To determine the mechanism whereby transient stimulation of the β-adrenergic receptor subtypes (β-AR) elicit cardioprotection against subsequent ischaemia. Isolated rat hearts were subjected to 35 min regional ischaemia (RI) and reperfusion and infarct size (IS) determined. Hearts were preconditioned with
Gao Shang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(27), 7780-7784 (2007-06-27)
Two beta-receptor agonists (-)-denopamine and (-)-arbutamine were prepared in good yields and enantioselectivities by asymmetric hydrogenation of unprotected amino ketones for the first time by using Rh catalysts bearing electron-donating phosphine ligands. A series of alpha-primary and secondary amino ketones
Weak arrhythmogenic property of the new cardiotonic agent denopamine in dogs: comparison with catecholamines
NARITA H, et al.
Japanese Journal of Pharmacology, 41(3), 335-344 (1986)
H Kurosawa et al.
Japanese journal of pharmacology, 72(4), 325-333 (1996-12-01)
Influence of cardiotonic agents on the prognosis of heart failure depends on the individual therapeutic agents, and favorable and unfavorable effects of these agents have been reported in clinical trials. We studied the effect of the cardiotonic agent denopamine on
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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