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重要文件

D6071

Sigma-Aldrich

Diphenylacetohydroxamic acid

≥98% (HPLC)

同義詞:

N-Hydroxy diphenylacetamide

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About This Item

經驗公式(希爾表示法):
C14H13NO2
CAS號碼:
分子量::
227.26
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

off-white to light tan

溶解度

DMSO: >20 mg/mL

儲存溫度

2-8°C

SMILES 字串

ONC(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C14H13NO2/c16-14(15-17)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13,17H,(H,15,16)

InChI 密鑰

OFSBBVCLWMCGNY-UHFFFAOYSA-N

生化/生理作用

Diphenylacetohydroxamic acid is a class IIa selective histone deacetylase inhibitor.

特點和優勢

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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存取文件庫

Douglas D Lemon et al.
FEBS letters, 589(10), 1080-1088 (2015-03-31)
PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors

文章

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

我們提供各種小分子研究工具,例如轉錄因子調節劑、染色質修飾酵素的抑制劑,以及用於基因調控研究中靶點鑑定和驗證的激效劑/拮抗劑;以下是這些研究工具的精選。

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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