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About This Item
經驗公式（希爾表示法）:
C21H34O4
CAS號碼:
分子量：:
350.49
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.77
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描述
solution in methyl acetate
形狀
liquid
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
CCCCC[C@H](O)\C=C\[C@H]1[C@@H]2CO[C@@H](C2)[C@@H]1C\C=C/CCCC(O)=O
InChI
1S/C21H34O4/c1-2-3-6-9-17(22)12-13-18-16-14-20(25-15-16)19(18)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18-,19+,20-/m0/s1
InChI 密鑰
DJKDIKIDYDXHDD-IGUVKOCZSA-N
生化／生理作用
Prostaglandin F2α analogue; thromboxane A2/prostaglandin H2 mimetic.
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
標靶器官
Central nervous system
安全危害
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
8.6 °F
閃點（°C）
-13 °C
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
I Mark Bowen et al.
The Journal of heart valve disease, 13(4), 593-599 (2004-08-18)
The equine aortic valve is subject to non-inflammatory degenerative changes, associated with aortic valvular regurgitation (AR). This disease shares pathological and epidemiological features with AR in humans, and may serve as a useful model to study in-vitro functional responses associated
J A Scott et al.
American journal of respiratory and critical care medicine, 154(3 Pt 1), 629-632 (1996-09-01)
Nonadrenergic noncholinergic (NANC) vasodilator mechanisms may contribute to the maintenance of low vascular resistance characteristic of the pulmonary circulation. Previous studies have demonstrated that nitric oxide (NO) is the principal NANC neurotransmitter in guinea pig pulmonary arteries. We examined whether
K Hayashi et al.
Journal of the American Society of Nephrology : JASN, 8(1), 25-31 (1997-01-01)
The thromboxane A2 (TXA2) mimetic U44069 has been demonstrated to reduce the GFR and filtration fraction of the normal isolated perfused rat kidney markedly, suggesting a predominant constriction of preglomerular vessels. To assess this possibility directly, effects of U44069 on
Pei-Yung Hsu et al.
Archives of biochemistry and biophysics, 416(1), 38-46 (2003-07-16)
Thromboxane A2 synthase (TXAS) binds to the endoplasmic reticulum membrane and catalyzes both an isomerization of prostaglandin H2 (PGH2) to form thromboxane A2 (TXA2) and a fragmentation of PGH2 to form 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and malondialdehyde (MDA). TXAS is a
G P Dubé et al.
The Journal of pharmacology and experimental therapeutics, 272(2), 799-807 (1995-02-01)
A novel thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor ligand, (+)5(Z)-7-[3-endo-phenylsulfonylamino[2.2.1]-bicyclohept-2-e xo- yl]-heptenoic acid [(+)-S-145], was evaluated in guinea pigs to assess the in vivo pharmacodynamic profile of this compound at vascular, cardiac and platelet TXA2/PGH2 receptors. Comparison was made to the
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