A2780 Cell Line human

93112519, human ovary, Epithelial

• 同義詞: A-2780 Cells
• 分類程式碼代碼: 41106514

屬性

• product name: A2780 Cell Line human, ovarian carcinoma, 93112519
• 生物源: human ovary
• 增長模式: Adherent
• 染色體組型: Not specified
• 形態學: Epithelial
• 產品: Not specified
• 受體: Not specified
• 技術: cell culture | mammalian: suitable
• 相關疾病: cancer
• 運輸包裝: dry ice
• 儲存溫度: −196°C

描述

細胞系來源

Human ovarian carcinoma

細胞系描述

The A2780 human ovarian cancer cell line was established from tumour tissue from an untreated patient. Cells grow as a monolayer and in suspension in spinner cultures. A2780 is the parent line to the cisplatin resistant cell line A2780 cis (Sigma catalogue no. 93112517) and the adriamycin resistant cell line A2780 ADR (Sigma catalogue no. 93112520).

應用

A2780 cell line human is used in toxicity testing and cancer genetic studies.
A2780 cell line human has been used to:

• study the role of Snail and Slug in ovarian tumor neovascularization
• overcome cisplatin resistance in ovarian cancer cells using liposome application
• demonstrate the significance of NMDA (N-methyl-D-aspartate) receptors as targets for treatment of ovarian cancers
• study the effect of low molecular weight heparin tinzaparin on cisplatin resistance in ovarian cancer cells

DNA分析

STR-PCR Data: Amelogenin: X
CSF1PO: 10,11
D13S317: 12,13
D16S539: 11,13
D5S818: 11,12
D7S820: 10
THO1: 6
TPOX: 8,10
vWA: 15,16

培養基

RPMI-1640 + 2mM Glutamine + 10% Foetal Boving Serum (FBS).

例行更新培養

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 3-6x10,000cells/cm² using 0.05% Trypsin or Trypsin/EDTA; 5% CO₂; 37°C.

其他說明

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

免責聲明

This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.