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重要文件

C9650

Sigma-Aldrich

β-氰基- L -丙氨酸

≥95%, suitable for ligand binding assays

同義詞:

3-cyano-L-alanine

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About This Item

經驗公式(希爾表示法):
C4H6N2O2
CAS號碼:
分子量::
114.10
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26
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產品名稱

β-氰基- L -丙氨酸, ≥95%

化驗

≥95%

形狀

powder

技術

ligand binding assay: suitable

顏色

white

mp

217 °C

儲存溫度

−20°C

SMILES 字串

OC([C@@H](N)CC#N)=O

InChI

1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1

InChI 密鑰

BXRLWGXPSRYJDZ-VKHMYHEASA-N

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生化/生理作用

β-氰基-L-丙氨酸 (BCA) 用作胱硫醚 γ-裂解酶 (CSE) 抑制剂,研究硫化氢在血管新生和高血压等过程中的生理作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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K Witthohn et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 79(1), 103-106 (1984-01-01)
Beside the known existence of cyanoglucosides (linamarin and lotaustralin) and proteins the neurotoxin beta-cyanoalanine has been demonstrated for the first time in the defensive secretions of animals. It is proposed that beta-cyanoalanine is produced by metabolizing cyanide from the cyanoglucosides.
Ying-Yuan Pamela Mok et al.
British journal of pharmacology, 143(7), 881-889 (2004-10-27)
Haemorrhagic shock (60 min) in the anaesthetized rat resulted in a prolonged fall in the mean arterial blood pressure (MAP) and heart rate (HR). Pre-treatment (30 min before shock) or post-treatment (60 min after shock) with inhibitors of cystathionine gamma
Tadahiko Masaki et al.
Journal of gastroenterology, 38(1), 37-44 (2003-02-01)
The clinical utility of relative and absolute grading criteria for submucosal invasion in T1 colorectal carcinomas has been controversial. In 51 T1 colorectal carcinomas, depth of submucosal invasion was graded either according to a modified Haggitt's classification (a relative criterion)
R Miura et al.
Journal of biochemistry, 87(5), 1469-1481 (1980-05-01)
The reaction of D-amino acid oxidase [EC 1.4.3.3] (DAO) from porcine kidney with beta-cyano-D-alanine (D-BCNA) was studied. DAO was found to catalyze elimination of the cyano group as well as oxidation of D-BCNA. During the course of the reaction in
Liping Fang et al.
Journal of hypertension, 27(11), 2174-2185 (2009-08-01)
Recently, periadventitial adipose tissue (PAT) was found to secrete bioactive factors playing an important role in the regulation of vascular tension. Hydrogen sulfide (H(2)S), a novel cardiovascular gasotransmitter, relaxes vessels through the K(ATP) channel in a calcium-dependent and endothelial-independent manner.

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