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Merck
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重要文件

C8849

Sigma-Aldrich

α-Chloralose−HBC complex

≥92% α-anomer basis

同義詞:

1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose: 2-hydroxypropyl-β-cyclodextrin complex

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.77
暫時無法取得訂價和供貨情況

品質等級

化驗

≥92% α-anomer basis

形狀

powder

儲存期限

4 weeks at 4 °C (for aqueous solutions)

溶解度

H2O: freely soluble

應用

α-Chloralose-HBC complex has been used for anesthetizing rats for various in vivo studies.[1][2][3]

生化/生理作用

α-Chloralose-HBC complex is a preferred anesthetic over isoflurane as it displays no intrusion retinal spreading depolarization (rSD) generation and propagation.[1]

品質

α-Chloralose content: 10% (w/w)

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type N95 (US)


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Tess E Kornfield et al.
eNeuro, 2(2) (2015-06-18)
Blood flow is a useful indicator of the metabolic state of the retina. However, accurate measurement of retinal blood flow is difficult to achieve in practice. Most existing optical techniques used for measuring blood flow require complex assumptions and calculations.
Anja I Srienc et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 36(9), 1579-1591 (2016-07-09)
Cortical spreading depolarization is a metabolically costly phenomenon that affects the brain in both health and disease. Following severe stroke, subarachnoid hemorrhage, or traumatic brain injury, cortical spreading depolarization exacerbates tissue damage and enlarges infarct volumes. It is not known
Kyle R Biesecker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(36), 9435-9445 (2016-09-09)
The brain is critically dependent on the regulation of blood flow to nourish active neurons. One widely held hypothesis of blood flow regulation holds that active neurons stimulate Ca(2+) increases in glial cells, triggering glial release of vasodilating agents. This
J Silverman et al.
Laboratory animal science, 43(3), 210-216 (1993-06-01)
Chloral hydrate (CH) and alpha-chloralose (CS) are often used to anesthetize laboratory animals although, to our knowledge, there have been no controlled studies of their anesthetic or analgesic effects. Induction of and recovery from anesthesia can be stressful, and anesthesia
Tess E Kornfield et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(34), 11504-11513 (2014-08-22)
Light stimulation evokes neuronal activity in the retina, resulting in the dilation of retinal blood vessels and increased blood flow. This response, named functional hyperemia, brings oxygen and nutrients to active neurons. However, it remains unclear which vessels mediate functional

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