推薦產品
化驗
≥98% (HPLC)
形狀
solid
儲存條件
desiccated
溶解度
DMSO: 24 mg/mL
儲存溫度
2-8°C
SMILES 字串
Oc1ccc(Cl)cc1N2C(SCC2=O)c3cccc(Br)c3
InChI
1S/C15H11BrClNO2S/c16-10-3-1-2-9(6-10)15-18(14(20)8-21-15)12-7-11(17)4-5-13(12)19/h1-7,15,19H,8H2
InChI 密鑰
KEGQNJITMFBVAC-UHFFFAOYSA-N
生化/生理作用
CK-548 inhibits the activity of actin-related protein (Arp)2/3 complex by inserting into the hydrophobic core of Arp3 and altering its conformation: inhibits
訊號詞
Warning
危險聲明
防範說明
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Renu Khasa et al.
Microbial pathogenesis, 149, 104565-104565 (2020-10-16)
Multiple membrane trafficking networks operate in the eukaryotic cell and are hijacked by viruses to establish infection. Recent studied have highlighted that viruses can exploit distinct pathways depending on the cell type. Japanese encephalitis virus (JEV), a neurotropic flavivirus, can
Renu Khasa et al.
The Journal of general virology, 100(2), 176-186 (2018-11-30)
Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is one of the leading global causes of virus-induced encephalitis. The infectious life-cycle of viruses is heavily dependent on the host membrane trafficking network. Here, we have performed a RNA-interference-based screen using a
Arnat Balabiyev et al.
Molecular biology of the cell, 31(18), 2002-2020 (2020-06-25)
Macrophage fusion resulting in the formation of multinucleated giant cells (MGCs) is a multistage process that requires many adhesion-dependent steps and involves the rearrangement of the actin cytoskeleton. The diversity of actin-based structures and their role in macrophage fusion is
Monika Hartmann et al.
Molecular cancer research : MCR, 13(5), 879-890 (2015-02-06)
Ectodomain cleavage (shedding) of transmembrane proteins by metalloproteases (MMP) generates numerous essential signaling molecules, but its regulation is not totally understood. CD44, a cleaved transmembrane glycoprotein, exerts both antiproliferative or tumor-promoting functions, but whether proteolysis is required for this is
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