C7493

Aminopurinyl pyranobenzopyranone 一水合物

≥98% (HPLC), solid

• 同義詞: (5aS,7S)-7-[2-(6-Amino-3H-purin-3-yl)-1-methylethyl]-5a,6,8,9-tetrahydro-3-methyl-1H,7H-pyrano[4,3-b]benzopyran-1-one 一水合物, CP2 一水合物
• 經驗公式（希爾表示法）: C₂₁H₂₃N₅O₃ · H₂O
• CAS號碼: 603113-07-1
• 分子量：: 411.45
• MDL號碼: MFCD11045285
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329775077
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 溶解度: DMSO: >10 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: O.C[C@H](Cn1cnc(N)c2ncnc12)[C@H]3CCC4=CC5=C(O[C@H]4C3)C=C(C)OC5=O
• InChI: 1S/C21H23N5O3.H2O/c1-11(8-26-10-25-19(22)18-20(26)24-9-23-18)13-3-4-14-6-15-17(29-16(14)7-13)5-12(2)28-21(15)27;/h5-6,9-11,13,16H,3-4,7-8,22H2,1-2H3;1H2/t11?,13-,16-;/m0./s1
• InChI 密鑰: WIRCSRUVUSUQDQ-HTIJIITDSA-N

描述

生化／生理作用

Aminopurinyl pyranobenzopyranone monohydrate is an inhibitor of Aβ oligomer-induced cytotoxicity. It is a new Alzheimer′s research tool and potential therapeutic agent.

Aminopurinyl pyranobenzopyranone monohydrate is an inhibitor of Aβ oligomer-induced cytotoxicity. It is a new Alzheimer′s research tool and potential therapeutic agent. Aminopurinyl pyranobenzopyranone monohydrate acts by inhibiting growth of Aβ oligomers and/or by preventing their toxic conformation or interaction with cellular substrates.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H300
• 防範說明: P264 - P301 + P310
• 危險分類: Acute Tox. 2 Oral
• 儲存類別代碼: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges