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Key Documents

C6696

Sigma-Aldrich

头孢菌素 来源于Cercospora hayii

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About This Item

經驗公式(希爾表示法):
C29H26O10
CAS號碼:
分子量::
534.51
MDL號碼:
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.85

形狀

solid

品質等級

溶解度

chloroform: 9.80- 10.20 mg/mL, clear, red to red-brown

抗生素活性譜

Gram-positive bacteria

作用方式

cell membrane | interferes

儲存溫度

2-8°C

SMILES 字串

COC1=C(CC(C)O)c2c3c(CC(C)O)c(OC)c(O)c4C(=O)C=C5OCOc6cc(O)c(C1=O)c2c6c5c34

InChI

1S/C29H26O10/c1-10(30)5-12-18-19-13(6-11(2)31)29(37-4)27(35)21-15(33)8-17-23(25(19)21)22-16(38-9-39-17)7-14(32)20(24(18)22)26(34)28(12)36-3/h7-8,10-11,30-32,35H,5-6,9H2,1-4H3

InChI 密鑰

JWFLIMIGORGZMQ-UHFFFAOYSA-N

應用

尾孢菌素(C29H26O10)是一种从香蕉病原体培养物中分离出来的红色色素。它已被用于研究野油菜黄单胞菌百日菊致病变种(Bacterium Xanthomonas campestris pv. Zinniae )等物种的毒素生物降解

生化/生理作用

头孢菌素是一种聚酮化合物植物毒素,可以被光激活,并在激活状态下与氧气反应生成有毒氧物种,例如单线态氧(O2)和超氧化物(O2-)。活性氧的产生导致植物细胞膜中脂质的过氧化。
据报道,光诱导的聚酮化合物植物毒素在光催化下会产生单线态氧。

其他說明

保存于密闭容器内,置于干燥通风处。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Sabine Butzloff et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 81(8), 698-703 (2012-06-28)
The malaria parasite Plasmodium falciparum proliferates within human erythrocytes and is thereby exposed to a variety of reactive oxygen species (ROS) such as hydrogen peroxide, hydroxyl radical, superoxide anion, and highly reactive singlet oxygen ((1)O(2)). While most ROS are already
Tanya V Taylor et al.
Applied and environmental microbiology, 72(9), 6070-6078 (2006-09-08)
The polyketide toxin cercosporin plays a key role in pathogenesis by fungal species of the genus Cercospora. The bacterium Xanthomonas campestris pv. zinniae is able to rapidly degrade this toxin. Growth of X. campestris pv. zinniae strains in cercosporin-containing medium
Barbara J Morgan et al.
Journal of the American Chemical Society, 131(26), 9413-9425 (2009-06-06)
The total syntheses of the PKC inhibitors (+)-calphostin D, (+)-phleichrome, cercosporin, and 10 novel perylenequinones are detailed. The highly convergent and flexible strategy developed employed an enantioselective oxidative biaryl coupling and a double cuprate epoxide opening, allowing the selective syntheses
Multiple modes of photodynamic action by cercosporin.
P E Hartman et al.
Photochemistry and photobiology, 47(5), 699-703 (1988-05-01)
Bang-Jau You et al.
Canadian journal of microbiology, 54(4), 259-269 (2008-04-05)
Cercosporin is a polyketide phytotoxin produced by many phytopathogenic Cercospora spp. We investigated environmental signals that have elaborate control of cercosporin production. Light is the most critical factor for cercosporin production. Cercospora nicotianae accumulated substantial quantities of cercosporin only when

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