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Merck
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重要文件

C5678

Sigma-Aldrich

羧甲基纤维素 钠盐

low viscosity

同義詞:

羧甲基纤维素钠

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25
暫時無法取得訂價和供貨情況

生物源

synthetic (organic)

形狀

powder

顏色

light yellow

有用的pH值範圍

(20 °C, 10 g/L, 68 °F neutral)

黏度

50-200 cP, 4 % in H2O(25 °C)

mp

> 300.05  °C ((> 572.09 °F ))

溶解度

water: soluble

正離子痕跡

Na: 6.5-9.5%

儲存溫度

room temp

SMILES 字串

[Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C

InChI

1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);

InChI 密鑰

DPXJVFZANSGRMM-UHFFFAOYSA-N

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一般說明

本品是一种低粘度羧甲基纤维素(CMC);其4%水溶液在25 oC下的粘度为50-200厘泊(cps)。粘度与浓度和温度有关。随着温度升高,粘度降低。随着浓度升高,粘度增加。低、中和高粘度羧甲基纤维素(CMC)均可用作助悬剂。低粘度CMC通常用作“稀”水溶液。 中等粘度CMC可使溶液像糖浆一样粘稠。 高粘度CMC用于制备类似于乳膏或乳液的混合物。

應用

可使用不同粘度的可溶性羧甲基纤维素(CM-纤维素; CMC)作为粘度调节剂(增稠剂),以稳定乳液并作为油和其他碳结构(如纳米管)的化学分散剂。CMC被用于开发生物结构产品,如生物膜、乳液和纳米颗粒药物递送系统。低粘度羧甲基纤维素可用于使溶液具有“稀”水溶液的黏稠度。[1]

準備報告

本品可溶于水(40 mg/mL)。溶解羧甲基纤维素的关键是将固体小心添加至水中,使其完全分散(充分润湿)。可能需要将固体分批添加至水中。 将水添加至干燥固体中会产生难以溶解的固体“团块”;因此必须将固体添加至水中。轻轻搅拌或间歇摇动;请勿使用磁力搅拌棒不断搅拌。无需高温,高温实际上可能减慢溶解过程。混合装置,如产生涡旋的叶轮型搅拌器,可将粉末卷入液体中,但是它可能会对粉末产生一些剪切作用。

在正常条件下,温度对本品溶液的影响是可逆的,因此轻微的温度变化对粘度没有持久影响。但是,长时间高温加热(高压灭菌)CMC溶液会使本品降解并永久性降低粘度。因此,CMC灭菌是非常困难的。与加热一样,γ-辐射也会降解CMC。与低粘度CMC相比,高压灭菌和辐照对高粘度CMC的不利影响更大。过滤CMC溶液往往会留下凝胶,因为该物质是纤维状的,所以溶液不能进行无菌过滤。

其他說明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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存取文件庫

R Farenzena et al.
Journal of animal physiology and animal nutrition, 101(5), 1057-1066 (2016-07-28)
Two in vivo digestibility trials with sheep were conducted to identify the minimum period length of feeding a new diet to obtain reproducible values of nutritional variables onward and the minimum length of collection period as to obtain maximal precision for
C Philippeau et al.
Journal of dairy science, 100(4), 2637-2650 (2017-02-06)
This study investigated the effects of bacterial direct-fed microbials (DFM) on ruminal fermentation and microbial characteristics, methane (CH
Shigenobu Mitsuzawa et al.
Scientific reports, 7(1), 16320-16320 (2017-11-28)
The glycoside hydrolase family 7 (GH7) member cellobiohydrolase (CBH) is a key enzyme that degrades crystalline cellulose, an important structural component of plant cell walls. As GH7 CBH is a major component in the enzyme mixture used to degrade biomass
Vinay Khatri et al.
Biotechnology for biofuels, 11, 144-144 (2018-05-26)
Pretreatment of lignocellulosic biomass (LCB) is a key step for its efficient bioconversion into ethanol. Determining the best pretreatment and its parameters requires monitoring its impacts on the biomass material. Here, we used fluorescent protein-tagged carbohydrate-binding modules method (FTCM)-depletion assay
Tim Wartewig et al.
Nature, 552(7683), 121-125 (2017-11-17)
T cell non-Hodgkin lymphomas are a heterogeneous group of highly aggressive malignancies with poor clinical outcomes. T cell lymphomas originate from peripheral T cells and are frequently characterized by genetic gain-of-function variants in T cell receptor (TCR) signalling molecules. Although

Questions

1–5 of 5 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is the carboxymethycelluose sterile?

    1 answer
    1. This product is not sterile.

      Helpful?

  4. I want to ask the degree of substitution of this CMC (C5678-500G). Thanks in advance.

    1 answer
    1. As mention on the Product Specification Sheet, the acceptable range / quality specification for Degree of Substitution is 0.65 - 0.90 carboxymethyl groups per anhydroglucose unit.

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  5. I want to know the molecualr weight of the Carboxymethylcellulose sodium salt low viscosity (C5678-500G)

    1 answer
    1. The molecular weight is not determined for each lot, however, historical information indicates a molecular weight of approximately 90 kDa.

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