推薦產品
生物源
Porcine intestinal mucosa
品質等級
化驗
≥90%
形狀
lyophilized powder
雜質
≤20% water (Karl Fischer)
顏色
white
溶解度
H2O: 5 mg/mL, clear, colorless
正離子痕跡
Na: 7.0-11.5%
儲存溫度
2-8°C
尋找類似的產品? 前往 產品比較指南
相關類別
一般說明
软骨素是一种糖胺聚糖(GAG),是N-乙酰半乳糖胺(GalNAc)和葡萄糖醛酸(GlcA)交替单元组成的多糖链,可以在GalNAc和GlcA其中一个单元或两个单元上发生硫酸化。软骨素及其硫酸盐经常与蛋白质结合形成蛋白多糖。硫酸软骨素B(硫酸软骨素)是蛋白聚糖的组分,例如核心蛋白聚糖,双糖链蛋白聚糖和多功能蛋白聚糖。硫酸软骨素B用于研究 β 肽(1-42)的细胞毒性。
應用
硫酸软骨素B可用于研究其作为生物分子受体、细胞信号传导和细胞结合分子的介质的作用。它可用于与硫酸软骨A和硫酸软骨素C的性质进行比较。硫酸软骨素B用于研究 β 肽(1-42)的细胞毒性。
生化/生理作用
作为一种大的带负电荷亲水性分子,硫酸软骨素分子不足以灵活折叠成紧密的球状结构,而是形成多孔水合凝胶,为组织提供机械支持,并允许水溶性分子的快速扩散和细胞迁移。
成分
硫酸软骨素B是在软骨、皮肤、角膜和脐带中发现的酸性粘多糖。 它由交替的N-乙酰半乳糖胺,L-艾杜糖醛酸和等摩尔量的硫酸盐残基组成,其中N-乙酰半乳糖胺的4位碳被硫酸化。
注意
请将该产品储存在2-8°C。
準備報告
将本产品 100 mg/mL的浓度溶于水。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
The Journal of rheumatology, 31(8), 1497-1505 (2004-08-04)
Pristane induced arthritis (PIA) is a seropositive experimental murine model that closely resembles rheumatoid arthritis (RA). Immune reactivity to a broad spectrum of autoantigens has been recognized in this disease model. We investigated the specificity of the autoimmune response in
International journal of molecular sciences, 19(6) (2018-06-09)
Oral mucositis is the most frequently occurring early side effect of head-and-neck cancer radiotherapy. Systemic dermatan sulfate (DS) treatment revealed a significant radioprotective potential in a preclinical model of oral mucositis. This study was initiated to elucidate the mechanistic effects
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 196(1), 85-94 (2019-11-11)
During head and neck cancer radiotherapy, oral mucositis is the most frequent early side effect. Systemic dermatan sulfate (DS) administration has been shown to significantly decrease oral mucosal radiation reactions during daily fractionated irradiation (IR) in an established mouse model.
Current Alzheimer research, 7(5), 428-438 (2010-01-02)
One mechanism leading to neurodegeneration during Alzheimer's disease (AD) is amyloid beta peptide (Abeta)-induced neurotoxicity. Among the factors proposed to potentiate Abeta toxicity is its covalent modification through carbohydrate-derived advanced glycation endproducts (AGEs). Other experimental evidence, though, indicates that certain
Macromolecular bioscience, 10(10), 1152-1163 (2010-05-19)
The amyloid-β peptide (Aβ) plays a central role in the mechanism of Alzheimer's disease, being the main constituent of the plaque deposits found in AD brains. Aβ amyloid formation and deposition are due to a conformational switching to a β-enriched
文章
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
瞭解更多關於糖胺聚醣和蛋白質聚醣的資訊,包括糖胺聚醣 (GAG) 的結構、不同類型的 GAG 及其功能。
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務