推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 27 kDa
物種活性
mouse, human, rat
技術
immunohistochemistry (frozen sections): 1:400 using frozen rat liver sections
western blot: 1:400 using a rat liver membrane preparation
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... GJB1(2705)
mouse ... Gjb1(14618)
rat ... Gjb1(29584)
一般說明
Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kDa. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. The 27kD connexin protein (connexin 32, Cx32) is expressed in several tissues.
免疫原
synthetic human connexin-32 peptide (amino acids 106-124).
應用
Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable for immunohistochemistry (frozen sections) at a dilution of 1:400 using frozen rat liver tissue. It is also suitable for western blot at a dilution of 1:400 using a rat liver membrane preparation.
Anti-Connexin-32 (106-124) antibody produced in rabbit has been used in:
- western blotting
- immunofluorescence
- immunohistology
生化／生理作用
Cx32 mutations is associated with X-linked Charcot-Marie-Tooth (CMTX) disease, which leads to myelin disruption and axonal degeneration.
外觀
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
The expression of mesenchymal, neural and haematopoietic stem cell markers in adult hepatocytes proliferating in vitro
Koenig S, et al.
Journal of Hepatology, 44(6), 1115-1124 (2006)
Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection
Rodriguez-Sinovas A, et al.
The Journal of Physiology, 588(7), 1139-1151 (2010)
Diego López et al.
Experimental physiology, 94(10), 1088-1097 (2009-07-21)
Previous studies demonstrated that intercellular communication through endothelial, smooth muscle or myoendothelial connexin channels contributes to the control of vascular tone. At least four connexin types are present in the arterial wall. The aim of the present work was to
Transient, recurrent, white matter lesions in X-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation
Hanemann CO, et al.
Archives of Neurology, 60(4), 605-609 (2003)
Cell junctions in the germinal epithelium may play an important role in spermatogenesis of the catfish P. fasciatum (Pisces, Siluriformes)
Batlouni SR, et al.
Journal of Molecular Histology, 36(1-2), 97-110 (2005)
文章
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
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