C3242

CDKi hydrochloride

≥98% (HPLC), solid

• 同義詞: 2,4-Diamino-5-oxo-pyrimidine hydrochloride
• 經驗公式（希爾表示法）: C₄H₆N₄O · xHCl
• CAS號碼: 70035-83-5
• 分子量：: 126.12 (free base basis)
• MDL號碼: MFCD08277042
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24724437

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 溶解度: H₂O: 21 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: Cl[H].Nc1ncc(O)c(N)n1
• InChI: 1S/C4H6N4O.ClH/c5-3-2(9)1-7-4(6)8-3;/h1,9H,(H4,5,6,7,8);1H
• InChI 密鑰: KEFSYBXFZWLDQU-UHFFFAOYSA-N

描述

生化／生理作用

CDKi hydrochloride is a potent and selective ATP competitiive inhibitor of cycB-CDK1, cycE-CDK2, and cycD1-CDK4. Demonstrates significant inhibitory activity against a variety of tumor type both in vitro and in vivo.

特點和優勢

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves