C111080

DMT-dC(bz)亚磷酰胺

configured for PerkinElmer, configured for Polygen

• 同義詞: DMT-dC(bz)酰胺, N-苯甲酰-5′-O-[双(4-甲氧苯基)苯甲基]-2′-脱氧胞苷, 3′-[2-氰乙基N,N-?双(1-甲基乙基)亚磷酰胺], N4-苯甲酰-5′-O-(4,4′-双甲氧基三基)-2′-脱氧胞苷-3′-O-[O-(2-氰乙基)-N,N′-二异丙基亚磷酰胺], 胞啶, N-苯甲酰-5′-O-[双(4-甲氧苯基)苯甲基]-2′-脱氧-, 3′-[2-氰乙基 双(1-甲基乙基)亚磷酰胺]
• 經驗公式（希爾表示法）: C₄₆H₅₂N₅O₈P
• CAS號碼: 102212-98-6
• 分子量：: 833.91
• MDL號碼: MFCD00036315
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329774852
• NACRES: NA.51

屬性

• 生物源: non-animal source (no BSE/TSE risk)
• 種類: for DNA synthesis
• 產品線: Proligo Reagents
• 化驗: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• 形狀: powder or granules
• 技術: oligo synthesis: suitable
• 雜質: ≤0.3 wt. % water content (Karl Fischer)
• 顏色: white to off-white
• &lambda ；: conforms (UV/VIS Identity)
• 相容性: configured for PerkinElmer; configured for Polygen
• 核苷譜: base: deoxycytidine; base protecting group: benzoyl; 2' protecting group: none; 5' protecting group: DMT; deprotection: standard
• 儲存溫度: 2-8°C
• SMILES 字串: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(=O)c4ccccc4)=NC3=O)(c5ccccc5)c6ccc(OC)cc6
• InChI: 1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1
• InChI 密鑰: PGTNFMKLGRFZDX-SALLYJDFSA-N

描述

一般說明

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites:

• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
• The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides

The product belongs to Expedite^™ synthesizers.

法律資訊

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable