L040080

Cap A

configured for PerkinElmer, configured for Polygen

• 分類程式碼代碼: 12352200
• NACRES: NA.21

屬性

• 種類: for DNA synthesis
• 產品線: Proligo Reagents
• 形狀: liquid
• 儲存條件: dry at room temperature
• 濃度: 88.7-108.4 g/L (Acetic Anhydride content, titration)
• 顏色: clear
• 相容性: configured for PerkinElmer; configured for Polygen

描述

一般說明

Cap A solution contains acetic anhydride and tetrahydrofuran (THF). It is used after the phosphoramidite reaction/coupling step.

生化／生理作用

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

準備報告

乙酸酐/四氢呋喃 9.1/90.9 (v/v)

安全資訊

• 象形圖: GHS02,GHS06,GHS08,GHS05
• 訊號詞: Danger
• 危險聲明: H225,H302,H315,H318,H331,H335,H336,H351
• 防範說明: P210 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• 危險分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Central nervous system, Respiratory system
• 安全危害: EUH019
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: -6.2 °F - closed cup
• 閃點（°C）: -21.2 °C - closed cup