跳轉至內容
Merck
全部照片(1)

重要文件

C0984

Sigma-Aldrich

肌酸激酶 MB 组分 来源于人类心脏

≥70% (SDS-PAGE), liquid

同義詞:

CK MB Fraction

登入查看組織和合約定價


About This Item

MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54
暫時無法取得訂價和供貨情況

生物源

human heart

品質等級

化驗

≥70% (SDS-PAGE)

形狀

liquid

濃度

≥0.5 mg/mL

技術

IR spectroscopy: suitable

適合性

suitable for tissue

UniProt登錄號

應用

pharmaceutical

儲存溫度

−20°C

基因資訊

尋找類似的產品? 前往 產品比較指南

一般說明

肌酸激酶(CK)由 M 和 B 亚基组成,是一种二聚合分子。它是一种 CK 同工酶。这种酶主要存在于心肌中。[1]

應用

来自人心的肌酸激酶 MB 已用于:
  • 作为急性心肌梗死的诊断标志物。[2]
  • 识别血液和心脏标志物的重叠吸收峰。[3]
  • 研究HIV-1感染的潜在治疗药物二氧戊环鸟苷(DXG)的体内磷酸化途径。[4]

生化/生理作用

肌酸激酶(CK)可催化从磷酸肌酸形成肌酸酐。[1]该酶与冠状动脉性能相关。CK-MB 血清水平升高是心肌细胞损伤的主要指标,[1]它被视作心肌梗死诊断的“金标准”。[1]心肌肌钙蛋白 I(cTnI)或心肌肌钙蛋白 I 的水平也与 CK-MB 水平升高相关。[5]慢性肾衰竭时 CK-MB 的水平也可能升高。[6]

成分

溶于 5 mM 琥珀酸钠、10 mM 氯化钠、1 mM EDTA、5 mMβ-巯基乙醇,50% 甘油,pH 7.0。

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Development and preliminary validation of infrared spectroscopic device for transdermal assessment of elevated cardiac troponin
Titus J, et al.
Communications medicine, 2 (2022)
J E Adams et al.
Clinical chemistry, 40(7 Pt 1), 1291-1295 (1994-07-01)
Although measurement of cardiac troponin I (cTnI) is, in some situations, more specific for detection of cardiac injury than is measurement of the MB isoenzyme of creatine kinase (MBCK), its sensitivity and specificity relative to MBCK for detection of myocardial
Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5?-phosphates by mammalian phosphotransferases
Feng JY, et al.
Biochemical Pharmacology, 68(9), 1879-1888 (2004)
Terry M Welsh et al.
Annals of clinical and laboratory science, 32(1), 44-49 (2002-02-19)
The diagnosis of myocardial infarction (MI) is established in patients with chest pain and equivocal electrocardiogram changes by demonstrating a rise in blood levels of creatine kinase MB (CK-MB) and/or an increase in cardiac troponin I (cTnI) or cardiac troponin
Creatine Kinase
Clinical Methods: The History, Physical, and Laboratory Examinations (1990)

Questions

1–2 of 2 Questions  
  1. What does the MB stand for in Product C0984, Creatine Kinase MB Fraction from human heart?

    1 answer
    1. Creatine Kinase is a dimer that exists as three isozymes: MM (muscle), MB (hybrid) and BB (brain).

      Helpful?

  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務