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Merck
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重要文件

B9680

Sigma-Aldrich

Bay u9773

≥98% (HPLC), oil

同義詞:

6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid

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About This Item

經驗公式(希爾表示法):
C27H36O5S
CAS號碼:
分子量::
472.64
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

oil

顏色

white

溶解度

DMSO: >25 mg/mL
ethanol: >25 mg/mL

起源

Bayer

運輸包裝

dry ice

儲存溫度

−70°C

SMILES 字串

CCCCC\C=C/C/C=C\C=C\C=C\[C@@H](Sc1ccc(cc1)C(O)=O)[C@@H](O)CCCC(O)=O

InChI

1S/C27H36O5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(28)15-14-17-26(29)30)33-23-20-18-22(19-21-23)27(31)32/h6-7,9-13,16,18-21,24-25,28H,2-5,8,14-15,17H2,1H3,(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t24-,25+/m0/s1

InChI 密鑰

PKJINWOACFYDQN-RBVMPENBSA-N

生化/生理作用

Subtype-selective cysteinyl-leukotriene (Cys-Lt) antagonist.

特點和優勢

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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S Ravasi et al.
Molecular pharmacology, 57(6), 1182-1189 (2000-05-29)
We report the identification of a novel pharmacological profile for the leukotriene (LT)C(4) binding site we previously identified in human lung parenchyma (HLP). We used a series of classic cysteinyl-LT (CysLT)(1) receptor antagonists belonging to different chemical classes and the

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