B7005

倍他米松

≥98%

• 同義詞: 9α-氟-11β,17α,21-三羟基-16β-甲基孕甾-1,4-二烯-3,20-二酮, 9α-氟-16β-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮, 9α-氟-16β-甲基泼尼松龙
• 經驗公式（希爾表示法）: C₂₂H₂₉FO₅
• CAS號碼: 378-44-9
• 分子量：: 392.46
• EC號碼: 206-825-4
• MDL號碼: MFCD00062969
• 分類程式碼代碼: 51111800
• PubChem物質ID: 57653954
• NACRES: NA.77

屬性

• 生物源: synthetic (organic)
• 無菌: non-sterile
• 化驗: ≥98%
• 形狀: powder
• mp: 235-237 °C (lit.)
• 溶解度: water: 0.063 g/L at 37 °C
• 運輸包裝: ambient
• 儲存溫度: room temp
• SMILES 字串: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI 密鑰: UREBDLICKHMUKA-DVTGEIKXSA-N
• 基因資訊: human ... ABCB1(5243) , CYP3A4(1576) , IL4(3565) , IL5(3567) , NR3C1(2908) ; mouse ... Abcb1a(18671) , Abcb1b(18669) , Ifng(15978) , Nos2(18126) , Tnf(21926) ; rat ... Ar(24208) , Nr3c1(24413) , Tnf(24835)

描述

應用

Betamethasone has been used as a corticosteroid (CORT) standard.[1]

生化／生理作用

Betamethasone, an isomer of dexamethasone is also termed as 9α-fluoro-16β-methyl-11 β,17,21-trihydroxypregna-1,4-dien-3,20-dione or 9α-fluoro-16β-methylprednisolone (27.1.52). It can be used as an anti-itch agent and treating dermatitis and eczema.[2]

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360FD,H373
• 防範說明: P201 - P202 - P260 - P280 - P308 + P313 - P405
• 危險分類: Repr. 1B - STOT RE 2
• 標靶器官: Liver,Kidney,Endocrine system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)