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Merck
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重要文件

AV100774

Sigma-Aldrich

Anti-FOXK2 (AB2) antibody produced in rabbit

IgG fraction of antiserum

同義詞:

Anti-Forkhead box K2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
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生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

69 kDa

物種活性

human

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... FOXK2(3607)

一般說明

FOXK2 belongs to the mammalian forkhead transcription factor family and contains forkhead DNA-binding domain and an FHA domain at the N-terminal region.[1]

免疫原

Synthetic peptide directed towards the C terminal region of human FOXK2

應用

Anti-FOXK2 (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 2.5 μg/ml.

生化/生理作用

FOXK2 plays an important regulatory role in AP-1 binding and AP-1 mediated gene expression.[1] It has been identified as regulator of IL-2 transcription[2] and is linked to cell cycle progression.[3] FOXK2 reportedly binds to DNA containing G/T mismatches with high affinity.[4]

序列

Synthetic peptide located within the following region: SASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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C Li et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(17), 7739-7743 (1991-09-01)
Human immunodeficiency virus (HIV) gene expression is regulated by both general transcription factors and factors induced by activation of T lymphocytes such as NF-kappa B and the nuclear factor of activated T cells (NFAT). Within the HIV long terminal repeat
Yoshito Fujii et al.
Journal of biochemistry, 147(5), 705-709 (2010-01-26)
DNA mismatch repair is an important mechanism in the prevention of mutations. We reported the existence in the HL60 cell line of a novel G/T-mismatch DNA-binding protein (nGTBP) requiring strict DNA sequences. In this report, we identify the FOXK2 transcription
Zongling Ji et al.
Molecular and cellular biology, 32(2), 385-398 (2011-11-16)
The transcriptional control circuitry in eukaryotic cells is complex and is orchestrated by combinatorially acting transcription factors. Forkhead transcription factors often function in concert with heterotypic transcription factors to specify distinct transcriptional programs. Here, we demonstrate that FOXK2 participates in
Anett Marais et al.
The Journal of biological chemistry, 285(46), 35728-35739 (2010-09-03)
Several mammalian forkhead transcription factors have been shown to impact on cell cycle regulation and are themselves linked to cell cycle control systems. Here we have investigated the little studied mammalian forkhead transcription factor FOXK2 and demonstrate that it is

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