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重要文件

A9434

Sigma-Aldrich

氯化铵

for molecular biology, suitable for cell culture, ≥99.5%

同義詞:

卤砂

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About This Item

線性公式:
NH4Cl
CAS號碼:
分子量::
53.49
Beilstein:
4371014
EC號碼:
MDL號碼:
分類程式碼代碼:
12352302
eCl@ss:
38050207
PubChem物質ID:
NACRES:
NA.31
化驗:
≥99.5%
等級:
for molecular biology
形狀:
powder or crystals
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等級

for molecular biology

品質等級

蒸汽密度

1.9 (vs air)

蒸汽壓力

1 mmHg ( 160.4 °C)

化驗

≥99.5%

形狀

powder or crystals

技術

cell culture | mammalian: suitable

mp

340 °C (subl.) (lit.)

負離子痕跡

phosphate (PO43-): ≤2 ppm
sulfate (SO42-): ≤20 ppm

正離子痕跡

Fe: ≤2 ppm
heavy metals (as Pb): ≤5 ppm

異物活動

DNase, RNase, protease, none detected

SMILES 字串

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI 密鑰

NLXLAEXVIDQMFP-UHFFFAOYSA-N

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應用

氯化铵已可用于:
  • 在vero细胞中作为内泌体酸化的抑制剂[1]
  • 作为血管平滑肌细胞(VSMC)的自噬抑制剂[2]
  • 在睾丸实质匀浆中红细胞的耗竭和裂解[3]

生化/生理作用

氯化铵是氮循环的三个主要成分之一。[4]氯化铵给药促进肌酐和尿素的清除[5] ,诱导小鼠代谢性酸中毒。[6]过量的氯化铵会抑制大脑中kreb′s通路,并耗尽星形胶质细胞中的ATP。[7]氯化铵抑制内溶酶体系统的酸化。[8]氯化铵是一种溶血剂,用于红细胞的溶解。[9]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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存取文件庫

Infectious bronchitis virus entry mainly depends on clathrin mediated endocytosis and requires classical endosomal/lysosomal system
Wang H, et al.
Virology, 528, 118-136 (2019)
Aqueous ammonia and ammonium chloride hydrates: Principal infrared spectra
Max JJ and Chapados C
Journal of Molecular Structure, 1046, 124-135 (2013)
Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. I. Renal function and biochemical changes
Jara A, et al.
Nephrology, Dialysis, and Transplantation, 19(8), 1986-1992 (2004)
Nrf2 Activation Provides Atheroprotection in Diabetic Mice Through Concerted Upregulation of Antioxidant, Anti-inflammatory, and Autophagy Mechanisms
Lazaro I, et al.
Frontiers in Pharmacology, 9, 118-136 (2018)
The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro
Haghighat N, et al.
Metabolic Brain Disease, 15(2), 151-162 (2000)

條款

The GenElute Mammalian Genomic DNA Purification Kit Protocol describes the isolation of pure, high molecular weight DNA from a variety of mammalian sources.

GenElute 哺乳动物基因组 DNA 纯化方案阐述了从多种哺乳动物来源中分离纯高分子量 DNA 的方法。

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What are the dimensions of the bottles for the following SKUs: A9434-1KG (Ammonium chloride) and A7906-500G (Bovine Serum Albumin)?

    1 answer
    1. The dimensions for the bottles are as follows:

      A9434-1KG:
      • 1.5 L warm (WM), white (WHT), High Density Polyethylene (HDPE) bottle (BTL) with a red polypropylene cap.
      • Length: 125mm
      • Width: 125mm
      • Weight: 124g
      • Height: 220mm
      • Height with Cap: 224mm
      • Weight of the cap: 35g
      • Thread Diameter of cap: 80mm
      • Thread Type of cap: 80mm

      A7906-500G:
      • 2.5 L warm (WM), white (WHT), High Density Polyethylene (HDPE) bottle (BTL) with a red polypropylene cap.
      • Length: 127mm
      • Weight: 158g
      • Width: 127mm
      • Height: 280mm
      • Height with Cap: 284mm
      • Thread Diameter of cap: 80mm
      • Thread Type of cap: 80mm
      • Weight of cap: 39g

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