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Merck
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重要文件

A8606

Sigma-Aldrich

Anti-α2C Adrenergic Receptor antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-α-2-adrenergic receptor, renal type, Anti-ADRA2C, Anti-ADRA2L2, Anti-ALPHA2CAR

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human, rat, mouse

濃度

~1 mg/mL

技術

immunohistochemistry: 1:100-1:300
western blot: 1:500-1:1,000

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ADRA2C(152)
mouse ... Adra2c(11553)
rat ... Adra2c(24175)

一般說明

Adrenergic receptors are a G-protein coupled receptors that exist in two forms, α or β. Ligands for adrenergic receptors are catecholamines that induce a sympathetic response in animal cells.
Studies have reported that α2C adrenergic receptors can regulate adrenergic opioid synergy and spinal analgesia. Rabbit Anti-α2C Adrenergic Receptor antibody binds to humanα2C Adrenergic Receptor.

免疫原

synthetic peptide corresponding to an internal sequence of human α2C Adrenergic Receptor.

應用

Rabbit Anti-α2C Adrenergic Receptor antibody can be used for immunohistochemistry (1:100-1:300) and western blot (1:500-1:1,000) applications.

外觀

solution in phosphate buffered saline, containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Carolyn A Fairbanks et al.
The Journal of pharmacology and experimental therapeutics, 300(1), 282-290 (2001-12-26)
The alpha(2A)-adrenergic receptor (AR) subtype mediates antinociception induced by the alpha(2)AR agonists clonidine, dexmedetomidine, norepinephrine, and 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine (UK-14,304) as well as antinociceptive synergy of UK-14,304 with opioid agonists [D-Ala(2),N-Me-Phe(4),Gly(5)-ol]-enkephalin and deltorphin II. Differential localization of alpha(2)-adrenergic (alpha(2A)-, alpha(2B)-(,) alpha(2C)-) and

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