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重要文件

A2504

Sigma-Aldrich

6-氨基己酸

≥99% (titration), powder

同義詞:

ε-氨基己酸, 6-氨基己酸, EACA

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About This Item

線性公式:
H2N(CH2)5CO2H
CAS號碼:
分子量::
131.17
Beilstein:
906872
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77
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生物源

synthetic

品質等級

化驗

≥99% (titration)

形狀

powder

技術

cell culture | mammalian: suitable

顏色

white

mp

207-209 °C (dec.) (lit.)

溶解度

H2O: 50 mg/mL

SMILES 字串

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

InChI 密鑰

SLXKOJJOQWFEFD-UHFFFAOYSA-N

基因資訊

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應用

EAC以25mg/ml溶解于水。因为是纤溶酶抑制剂,它被用在纤维蛋白酶分析凝血缓冲液。缓冲液是10mM磷酸钾和磷酸钠,pH6.4,再加上0.20gCaCl2, 5g 6-氨基己酸,1g叠氮化钠和9g氯化钠,都溶解在1升体系里。缓冲液在室外下无限期稳定。

生化/生理作用

EACA被报道能够抑制糜蛋白酶、因子VIIA、赖氨酸碳氧基肽酶、纤溶酶,纤溶酶原激活物。
赖氨酸类似物。促进纤溶酶的快速解离,从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。据报道可抑制纤溶酶原与活化的血小板结合。 早期报告表明,它抑制补体系统第一成分的激活。结合羧肽酶 B并使其灭活。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

404.6 - 408.2 °F

閃點(°C)

207 - 209 °C

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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E M Van Hoeyveld et al.
The Journal of allergy and clinical immunology, 76(4), 543-550 (1985-10-01)
The effect of epsilon-aminocaproic acid (EACA) on the degradation of an aqueous Lolium perenne extract was studied by intracutaneous tests and by RAST inhibition. Extracts for skin testing stored at 4 degrees C for 12 months and at 37 degrees
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Adenosine A2A receptor mediates the promotion of wound healing and revascularization of injured tissue, in healthy and animals with impaired wound healing, through a mechanism depending upon tissue plasminogen activator (tPA), a component of the fibrinolytic system. In order to

文章

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

分析酵素 Chymotrypsin:糜蛋白酶在胰腺的胰腺尖細胞中以非活性前體糜蛋白酶原的形式產生。

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