73156

N-Methyl-L-serine

≥98% (TLC)

• 同義詞: (S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
• 經驗公式（希爾表示法）: C₄H₉NO₃
• CAS號碼: 2480-26-4
• 分子量：: 119.12
• Beilstein: 2498641
• MDL號碼: MFCD00037756
• 分類程式碼代碼: 12352202
• PubChem物質ID: 329764666
• NACRES: NA.32

屬性

• 化驗: ≥98% (TLC)
• 形狀: powder
• 光學活性: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• 成份: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• 顏色: white
• mp: 204 °C
• SMILES 字串: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
• InChI 密鑰: PSFABYLDRXJYID-VKHMYHEASA-N

描述

生化／生理作用

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease[1], neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts[2].

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids. [2]

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable