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重要文件

72335

Sigma-Aldrich

9-(2,2-二氰乙烯基)久洛啶

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

同義詞:

9-久洛啶基亚甲基丙二腈, DCVJ

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About This Item

經驗公式(希爾表示法):
C16H15N3
CAS號碼:
分子量::
249.31
Beilstein:
413882
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.32
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產品線

BioReagent

化驗

≥97.0% (HPLC)

形狀

crystals

溶解度

DMSO: soluble
chloroform: soluble

螢光

λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol

適合性

suitable for fluorescence

SMILES 字串

N#C\C(=C/c1cc2CCCN3CCCc(c1)c23)C#N

InChI

1S/C16H15N3/c17-10-13(11-18)7-12-8-14-3-1-5-19-6-2-4-15(9-12)16(14)19/h7-9H,1-6H2

InChI 密鑰

LROAUBRDKLVBCP-UHFFFAOYSA-N

包裝

无底玻璃瓶。内容物在插入式融锥内。

其他說明

作为荧光探针,用于结合蛋白质等,通过减少自由旋转来增加量子产率;吸收波长在~450nm处,发射波长在480-505nm处(溶剂dep.)[1][2]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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C E Kung et al.
Biochemistry, 28(16), 6678-6686 (1989-08-08)
9-(Dicyanovinyl)julolidine (DCVJ) is a fluorescent dye whose intramolecular rotational relaxation is solvent dependent. Since its quantum yield increases with decreasing free volume, this molecule has been very useful in monitoring synthetic polymer reactions and measuring local microviscosity changes in phospholipid
Christian Lubich et al.
Pharmaceutical research, 32(9), 2863-2876 (2015-03-20)
Sub-visible particles were shown to facilitate unwanted immunogenicity of protein therapeutics. To understand the root cause of this phenomenon, a comprehensive analysis of these particles is required. We aimed at establishing a flow-cytometry-based technology to analyze the amount, size distribution
T Furuno et al.
Immunology letters, 33(3), 285-288 (1992-08-01)
A confocal fluorescence microscope was used to study the exocytotic secretory processes of mast cells in combination with an fluorescent molecular rotor, 9-(dicyanovinyl)julolidine (DCVJ). DCVJ is known to be an unique fluorescent dye which increases its quantum yield with decreasing
Markus J Schmidt et al.
Journal of biological engineering, 11, 24-24 (2017-08-09)
The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a previously reported photoisomeric behavior may contribute to the measured fluorescence intensity
T Iio et al.
Journal of biochemistry, 109(4), 499-502 (1991-04-01)
A molecular rotor, 9-(dicyanovinyl)julolidine (DCVJ), is a fluorescent dye whose intramolecular rotation determines its fluorescence yield [Kung, C.E. & Reed, J.K. (1989) Biochemistry 28, 6678-6686]. DCVJ binds to bovine brain calmodulin and emits strong fluorescence. In fluorescence titration experiments, the

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