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57510

Sigma-Aldrich

肌苷-5′-单磷酸 二钠盐 水合物

≥99.0% (HPLC)

同義詞:

5 & # 8242;-肌苷酸 二钠盐 水合物, 5′-IMP-Na2, I-5′-P, IMP, 肌苷酸

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About This Item

經驗公式(希爾表示法):
C10H11N4O8PNa2 · xH2O
CAS號碼:
分子量::
392.17 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

化驗

≥99.0% (HPLC)

形狀

powder or crystals

光學活性

[α]20/D −32±2°, c = 1% in H2O

雜質

~25% water

SMILES 字串

[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI 密鑰

KQCIGEIXDXQSGM-MSQVLRTGSA-L

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相關類別

應用

肌苷-5′-单磷酸盐 (5'-IMP) 可作为研究肌苷 5′ 的活性、特异性和动力学的底物-单磷酸脱氢酶 (IMPDH) 酶代码 EC 1.1.1.205,GMP 形成的限速酶和鸟嘌呤核苷酸池。

生化/生理作用

肌苷一磷酸或肌苷酸是次黄嘌呤的核糖核苷酸,是嘌呤合成过程中形成的第一个核苷酸。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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International immunopharmacology, 10(1), 91-97 (2009-10-21)
Inosine 5'-monophosphate dehydrogenase (IMPDH) inhibition is a critical target in solid organ transplantation, and the development of mycophenolate mofetil (MMF) represents a major advance in transplant medicine. In this study, the in vitro and in vivo pharmacological effects of BMS-566419
L Hedstrom et al.
Current medicinal chemistry, 18(13), 1909-1918 (2011-04-27)
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