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56741

Supelco

IGEPAL® CA-630

同義詞:

Nonidet P 40, 壬基苯酚-聚乙二醇醚, 辛基苯氧基聚乙烯氧乙醇,支链, 聚氧乙烯辛烷基苯酚醚,分支, 辛基苯基-聚乙烯二醇

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About This Item

線性公式:
(C2H4O)nC14H22O
CAS號碼:
MDL號碼:
分類程式碼代碼:
12161902
NACRES:
NA.25
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描述

non-ionic

形狀

liquid

分子量

~603.0 g/mol

折射率

n20/D 1.492

CMC

0.08 mM (20-25°C)

轉變溫度

cloud point 63-67  °C

密度

1.06 g/mL at 20 °C

負離子痕跡

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

正離子痕跡

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤1000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

HLB

13

SMILES 字串

O(CCO)c1ccc(cc1)C(CC(C)(C)C)(C)C

InChI

1S/C16H26O2/c1-15(2,3)12-16(4,5)13-6-8-14(9-7-13)18-11-10-17/h6-9,17H,10-12H2,1-5H3

InChI 密鑰

JYCQQPHGFMYQCF-UHFFFAOYSA-N

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一般說明

IGEPAL ® CA-630 是一种非离子型、非变性去污剂,适用于膜蛋白复合物的增溶、分离和纯化。化学上与 Nonidet P-40 难以区分。[1]

應用

IGEPAL ® CA-630已被用于:
  • 在用于抗原表位标记的 HAGγ 1HAGγ1C71S 下拉分析的光导蛋白共沉淀试验中[2]
  • 作为用于细胞培养和MAPK(丝裂原活化蛋白激酶)分析和免疫印迹的样品制备的裂解缓冲液的组分[3][4]
  • 在油红 O 染色程序中提取细胞,以可视化脂肪形成过程中细胞中的脂质形成[4]
  • 作为含 Tris-HCl、NaCl 和 EDTA 的裂解缓冲液组分用于免疫印迹实验[5]

其他說明

非离子型、非变性洗涤剂

品質

在化学性质方面,不能与已经退市的 Nonidet P-40 区分开。

注意

储存时可能变得浑浊;加热至 40℃ 可得到澄清产物。
在贮存过程中可能产生混浊或沉淀物。 可在加热至时40°C变为澄清液体。

法律資訊

IGEPAL is a registered trademark of Solvay
Nonidet is a trademark of Shell Chemical Co.

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

483.8 °F - closed cup

閃點(°C)

251 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Selective mutations in estrogen receptor alpha' s D-domain alters nuclear translocation and non-ERE gene regulatory mechanisms.
Burns K A, et al.
The Journal of Biological Chemistry, jbc-M110 (2011)
Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors.
Frontiers in Molecular Neuroscience, 11, 16-16 (2018)
MEK?ERK and heparin-susceptible signaling pathways are involved in cell-cycle entry of the wound edge retinal pigment epithelium cells in the adult newt.
Yoshikawa T, et al.
Pigment Cell & Melanoma Research, 25(1), 66-82 (2012)
Regulation of ERRa gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by G protein-coupled receptor GPR30/GPER-1.
Li Y, et al.
Molecular Endocrinology, 24(5), 969-980 (2010)
Arun K Mishra et al.
Molecular microbiology, 80(5), 1241-1259 (2011-03-26)
Lipomannan (LM) and lipoarabinomannan (LAM) are key Corynebacterineae glycoconjugates that are integral components of the mycobacterial cell wall, and are potent immunomodulators during infection. LAM is a complex heteropolysaccharide synthesized by an array of essential glycosyltransferase family C (GT-C) members

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. what is the concentration of this IGEPAL® CA-630 solution ?

    1 answer
    1. This product is considered a neat chemical, so you may assume 100% in your calculations.

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