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Merck
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重要文件

49095

Sigma-Aldrich

2-Acetamido-2-deoxy-6-O-(α-L-fucopyranosyl)-D-glucopyranose

≥98.0% (TLC)

同義詞:

2-Acetamido-2-deoxy-6-O-(6-deoxy-α-L-galactopyranosyl)-D-glucopyranose, Fucosyl-α-1,6-N-acetylglucosamine

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About This Item

經驗公式(希爾表示法):
C14H25NO10
分子量::
367.35
分類程式碼代碼:
12352200
PubChem物質ID:
暫時無法取得訂價和供貨情況

化驗

≥98.0% (TLC)

儲存溫度

−20°C

SMILES 字串

O[C@H]1[C@H](O)[C@@H](NC(C)=O)C(O)O[C@@H]1CO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O

InChI

1S/C14H25NO10/c1-4-8(17)11(20)12(21)14(24-4)23-3-6-9(18)10(19)7(13(22)25-6)15-5(2)16/h4,6-14,17-22H,3H2,1-2H3,(H,15,16)/t4?,6?,7-,8+,9+,10?,11?,12+,13+,14+/m0/s1

InChI 密鑰

BSNVYGSAFLBSSQ-ZXPKOIJOSA-N

應用

Disaccharide for testing alpha-1,6-fucosylation of N-acetylglucosamine

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Naoyuki Taniguchi et al.
Current opinion in structural biology, 16(5), 561-566 (2006-09-15)
Identification of the glycosyltransferase genes that are involved in the biosynthesis of glycoconjugates has opened up new avenues in glycobiology, the decoding of the function of sugar chains. Specific biosynthesis of branched N-glycan structures by glycosyltransferases functionally modifies target glycoproteins
Antônia S F do Nascimento et al.
Glycobiology, 25(6), 607-616 (2015-01-13)
We determined the specificity of BTL, a lectin from the red marine alga Bryothamnion triquetrum, toward fucosylated oligosaccharides. BTL showed a strict specificity for the core α1,6-fucosylation, which is an important marker for cancerogenesis and quality control of therapeutical antibodies.
Xue-En Liu et al.
Hepatology (Baltimore, Md.), 46(5), 1426-1435 (2007-08-09)
We evaluated the use of blood serum N-glycan fingerprinting as a tool for the diagnosis of hepatocellular carcinoma (HCC) in patients with cirrhosis induced by hepatitis B virus (HBV). A group of 450 HBV-infected patients with liver fibrosis or cirrhosis
E Staudacher et al.
European journal of biochemistry, 199(3), 745-751 (1991-08-01)
Incubation of honeybee (Apis mellifica) venom-gland extracts with GDP-[14C]fucose and GlcNAc beta 1----2Man alpha 1----6(GlcNAc beta 1----2Man alpha 1----3)Man beta 1----4GlcNAc beta 1----4(Fuc alpha 1----6)GlcNAc beta 1----N-Asn-peptide(NAc) gave a labeled product in 40% yield. Analysis by 500-MHz 1H-NMR spectroscopy indicated
N Kojima et al.
Journal of biochemistry, 124(4), 726-737 (1998-10-02)
To determine the effect of alpha1,6-linked fucose modification of N-glycans on the expression of polysialic acids (PSAs), the expression of PSAs in a fucose-lacking mutant of Chinese hamster ovary (CHO) cells, Lec13, was compared with that in CHO K1 cells.

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