推薦產品
生物源
mouse
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
B72.3, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (337M-84)
vial of 0.5 mL concentrate (337M-85)
bottle of 1.0 mL predilute (337M-87)
vial of 1.0 mL concentrate (337M-86)
bottle of 7.0 mL predilute (337M-88)
製造商／商標名
Cell Marque®
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同型
IgG1κ
控制
lung adenocarcinoma
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic
一般說明
Anti-B72.3 recognizes a high molecular weight glycoprotein called TAG-72 that is present in human adenocarcinomas and in lesser amounts, non-neoplastic tissues. It has also been found to be useful to distinguish between mesothelioma and adenocarcinoma, however, false positive reactions can occur so results must be interpreted with the utmost caution.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
TAG-72 Positive Control Slides, Product No. 337S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: [email protected]
法律資訊
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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分析證明 (COA)
Lot/Batch Number
W W Johnston et al.
Human pathology, 17(5), 501-513 (1986-05-01)
Monoclonal antibody B72.3 has been shown to be reactive with a high-molecular-weight glycoprotein complex termed TAG(tumor-associated glycoprotein)-72. By the avidin-biotin immunoperoxidase method, fine needle aspirates and corresponding surgically excised tumor tissues from both malignant and benign tissues were analyzed for
K G Osteen et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 11(3), 216-220 (1992-07-01)
Compared with the degree of investigation of stage-specific expression of tumor-associated glycoprotein-72 (TAG-72) in fundal endometrium, other regions of the female reproductive tract have not received comparable attention. Regional, cell-type-specific, and temporal differences in estrogen receptor and progesterone receptor distribution
A Thor et al.
Cancer research, 46(6), 3118-3124 (1986-06-01)
Murine monoclonal antibody B72.3, prepared against a membrane-enriched extract of human metastatic carcinoma, was reacted with a spectrum of adult and fetal human tissues using avidin-biotin-complex immunohistochemical techniques to evaluate the expression of the reactive tumor associated glycoprotein (TAG)-72 antigen.
The use of Mab B72.3 in the diagnosis of human carcinoma
Schlom J, et al.
J. Tumor Marker oncol., 2, 95-112 (1987)
David C Chhieng et al.
Human pathology, 34(10), 1016-1021 (2003-11-11)
Ovarian carcinoma has a high mortality rate, because most ovarian carcinomas are detected at a late stage. Traditional therapies, such as surgical debulking and chemotherapy, have not been successful in improving the long-term survival of these patients. Alternative therapies targeting
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