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270458

Sigma-Aldrich

NMP

suitable for HPLC, ≥99%

同義詞:

N-甲基-2-吡咯烷酮, N-甲基吡咯烷酮, NMP

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About This Item

經驗公式（希爾表示法）:
C5H9NO
CAS號碼:
872-50-4
分子量：:
99.13
Beilstein:
106420
EC號碼:
212-828-1
MDL號碼:
MFCD00003193
分類程式碼代碼:
12190000
PubChem物質ID:
329752940
NACRES:
NA.21
bp:
202 °C (lit.)
81-82 °C/10 mmHg (lit.)
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產品名稱

1-甲基-2-吡咯烷酮, suitable for HPLC, ≥99%

等級

HPLC grade

蒸汽密度

3.4 (vs air)

蒸汽壓力

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

化驗

≥99%

形狀

liquid

自燃溫度

518 °F

純化經由

glass distillation

expl. lim.

9.5 %

技術

HPLC: suitable

雜質

<0.050% water

顏色

APHA: ≤10

折射率

n20/D 1.47 (lit.)

pH值

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

密度

1.028 g/mL at 25 °C (lit.)

&lambda ；

H2O reference

紫外吸收

λ: 285 nm Amax: 1.00
λ: 300 nm Amax: 0.50
λ: 325 nm Amax: 0.10
λ: 350-400 nm Amax: 0.01

應用

food and beverages

SMILES 字串

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI 密鑰

SECXISVLQFMRJM-UHFFFAOYSA-N

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相關類別

一般說明

1-甲基-2-吡咯烷酮，一种叔酰胺，[1] 广泛用作有机溶剂。[2]它参与高质量MOF（金属有机骨架）-177晶体的声化学合成。[3]
它还参与以下过程：[1]
  • 氰基三甲基硅烷的合成
  • 醛类的脱羰基反应
  • 将苯甲醛和酮还原成相应的醇
  • 天然产品的制备

應用

1-甲基-2-吡咯烷酮（NMP）已被用作溶剂以研究丙烯酸酯聚合物对石墨烯的分散能力。[2]在一项研究中，它还被用于制造用于电化学测量的工作电极。[4]

包裝

M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!

推薦產品

探索最适于 HPLC 或 LC-MS 分析的 LiChropur 试剂

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Danger

危險分類

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 1

閃點（°F）

195.8 °F - Pensky-Martens closed cup

閃點（°C）

91 °C - Pensky-Martens closed cup

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
SHBS4183
SHBR4152
SHBR8272
SHBR6965
SHBR4803

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存取文件庫

High-yield exfoliation of graphite in acrylate polymers: A stable few-layer graphene nanofluid with enhanced thermal conductivity.
Sun Z, et al.
Carbon, 64(23), 288-294 (2013)
Direct Observation of Reversible Magnesium Ion Intercalation into a Spinel Oxide Host.
Chunjoong Kim et al.
Advanced materials (Deerfield Beach, Fla.), 27(22), 3377-3384 (2015-04-18)
1-Methyl-2-pyrrolidinone.
Trapencieris P and Pigza JA.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2009)
Da-Won Jung et al.
Dalton transactions (Cambridge, England : 2003), 39(11), 2883-2887 (2010-03-05)
High quality MOF-177 crystals in the size range of 5-20 microm were successfully synthesized via a sonochemical route in a substantially reduced synthesis time (40 min) in the presence of low-cost NMP (1-methyl-2-pyrrolidone) as a solvent. Microwave heating in NMP
David S Hewings et al.
Journal of medicinal chemistry, 54(19), 6761-6770 (2011-08-20)
Histone-lysine acetylation is a vital chromatin post-translational modification involved in the epigenetic regulation of gene transcription. Bromodomains bind acetylated lysines, acting as readers of the histone-acetylation code. Competitive inhibitors of this interaction have antiproliferative and anti-inflammatory properties. With 57 distinct
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1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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