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重要文件

Y0001161

卡巴匹林杂质B

European Pharmacopoeia (EP) Reference Standard

同義詞:

2-[[[2-(乙酰氧基)苯甲酰基]氧基]苯甲酸, 2-羧苯基o- 乙酰水杨酸酯

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About This Item

經驗公式(希爾表示法):
C16H12O6
CAS號碼:
分子量::
300.26
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

carbasalate

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

O(c1c(cccc1)C(=O)Oc2c(cccc2)C(=O)O)C(=O)C

InChI

1S/C16H12O6/c1-10(17)21-14-9-5-3-7-12(14)16(20)22-13-8-4-2-6-11(13)15(18)19/h2-9H,1H3,(H,18,19)

InChI 密鑰

DDSFKIFGAPZBSR-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Carbasalate impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

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分析證明 (COA)

Lot/Batch Number

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F E Blondino et al.
Journal of pharmaceutical and biomedical analysis, 13(2), 111-119 (1995-02-01)
Formulation of pressurized aerosol solutions in propellants for inhalation requires the use of high quantities of surfactants to solubilize the drug. Due to the lipophilic nature of these surfactants, analytical difficulties are created for those wishing to quantify the drug
P V Mroso et al.
Journal of pharmaceutical sciences, 71(10), 1096-1101 (1982-10-01)
Salicylsalicylic acid and acetylsalicylsalicylic acid were identified as decomposition products of aspirin when mixtures of the drug, with magnesium stearate, were stored in the solid state of 60 degrees and 75% relative humidity. The effect of increasing the concentration of
Tamás Fischer
Orvosi hetilap, 150(11), 503-512 (2009-03-05)
The beneficial effect achieved by the treatment of endothelial dysfunction in chronic cardiovascular diseases is already an evidence belonging to the basic treatment of the disease. Given the fact that the vascular system is uniform and consubstantial both physiologically, pathophysiologically
R D Kirchhoefer et al.
Journal of pharmaceutical sciences, 69(5), 550-553 (1980-05-01)
A quantitative high-pressure liquid chromatographic method, using a reversed-phase column and an aqueous acetic acid-methanol solution as the mobile phase, was employed for the determination of O-acetyl-O-salicylsalicylic acid and O-salicylsalicylic acid in pharmaceutical aspirin preparations. The aspirin was dissolved, filtered
Hydrolysis of acetylsalicylsalicylic acid and salicylsalicylic acid in aqueous solution.
H Sunada et al.
Chemical & pharmaceutical bulletin, 33(5), 2158-2161 (1985-05-01)

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