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重要文件

X100PC

Sigma-Aldrich

Triton X-100

peroxide- and carbonyl-free

同義詞:

4-(1,1,3,3-四甲基丁基)苯基-聚乙二醇, t-辛基苯氧基聚乙氧基乙醇, 聚乙二醇 辛基苯醚

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About This Item

線性公式:
t-Oct-C6H4-(OCH2CH2)xOH, x= 9-10
CAS號碼:
Beilstein:
2315025
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.25
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描述

non-ionic

品質等級

形狀

liquid

分子量

micellar avg mol wt 80,000
average mol wt 625

包裝

ampule of 5, 5x5, 10x5 mL

凝集数

100-155

CMC

0.2-0.9 mM (20-25°C)

轉變溫度

cloud point 65 °C
pour point ~7 °C

溶解度

water: soluble

HLB

13.5

SMILES 字串

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI 密鑰

HNLXNOZHXNSSPN-UHFFFAOYSA-N

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一般說明

Triton X-100 是一种常见的非离子表面活性剂和乳化剂,常用在生化应用中溶解蛋白质。它是相对温和的洗涤剂,非变性,据报道,在许多参考文献中被用作常规添加剂。它用于裂解细胞、提取蛋白质和细胞器。它还可以增强活细胞可渗透性,便于转染。[1][2]

應用

0·3% Triton X-100 TBS 溶液已用于免疫染色前视网膜的透化。[3][4] 0.5% Triton X-100 已用于星形胶质细胞裂解。[5]

生化/生理作用

广泛使用的非离子型表面活性剂,用于在温和的非变性条件下回收膜组分。

包裝

氩气保护下安瓿包装。

法律資訊

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

483.8 °F - closed cup

閃點(°C)

251 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Cytotoxicity of bilirubin for human fibroblasts and rat astrocytes in culture. Effect of the ratio of bilirubin to serum albumin.
Chuniaud L, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 256(2), 103-114 (1996)
Quantitative ex vivo detection of rodent retinal ganglion cells by immunolabeling Brn-3b.
Experimental Eye Research, 79(1), 131-140 (2004)
Adeno-associated virus mediated SOD gene therapy protects the retinal ganglion cells from chronic intraocular pressure elevation induced injury via attenuating oxidative stress and improving mitochondrial dysfunction in a rat model.
American Journal of Translational Research, 8(2), 799-799 (2016)
The size, shape, and hydration of nonionic surfactant micelles. Triton X-100.
Robson RJ and Dennis EA
The Journal of Physical Chemistry, 81, 1075-1078 (1977)
Friederike Pfeiffer et al.
Acta neuropathologica, 122(5), 601-614 (2011-10-11)
In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), loss of the blood-brain barrier (BBB) tight junction (TJ) protein claudin-3 correlates with immune cell infiltration into the CNS and BBB leakiness. Here we show that sealing BBB

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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