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Merck
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Key Documents

P2472

Sigma-Aldrich

聚维酮

meets USP testing specifications

同義詞:

聚乙烯吡咯烷酮, PVP, 聚维酮

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About This Item

線性公式:
(C6H9NO)n
CAS號碼:
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.21

agency

USP/NF
meets USP testing specifications

品質等級

描述

K-value 29 - 32

形狀

powder

應用

pharmaceutical (small molecule)

SMILES 字串

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI 密鑰

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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應用


  • Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.: This study highlights the application of povidone (PVP) in the synthesis of multifunctional nanodrugs, showcasing its role in stabilizing nanoparticles for targeted cancer therapy. The findings emphasize PVP′s crucial function in enhancing the bioavailability and therapeutic efficacy of anticancer drugs (Wang C et al., 2024).

其他說明

聚乙烯吡咯烷酮是 Denhardt′s 溶液的一种成分,在标准 50X 储备溶液中的浓度为 1%(w/v)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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Markéta Julinová et al.
Water environment research : a research publication of the Water Environment Federation, 84(12), 2123-2132 (2013-01-25)
Polyvinylpyrrolidone (PVP) is a frequently used polymer in the pharmaceutical and foodstuff industries. Because it is not subject to metabolic changes and is virtually nondegradable, trace concentrations of PVP are often found in community wastewaters. The literature finds that the
X C Qin et al.
Journal of photochemistry and photobiology. B, Biology, 120, 156-162 (2013-01-30)
Nanographene oxide (NGO), a new type of nanomaterial for anticancer drugs delivery and near-infrared (NIR)-mediated photothermal ablation of tumors, has been used in the combination of photothermal therapy and chemotherapy. Herein, targeted chemo-photothermal therapy based on polyvinylpyrrolidone (PVP) functionalized NGO
Sung Neung Lee et al.
Archives of pharmacal research, 36(1), 79-85 (2013-01-19)
A novel surface-attached, spray-dried solid dispersion containing poorly water-soluble carvedilol (CV) without any change in the crystallinity was prepared using water, polyvinylpyrrolidone (PVP K30) and Tween 80. The solid dispersion was optimized by investigating the effects of the weight ratios
Amrit Paudel et al.
Journal of pharmaceutical sciences, 102(4), 1249-1267 (2013-01-30)
The present study investigates the effect of changing spray drying temperature (40°C-120°C) and/or atomizing airflow rate (AR; 5-15 L/min) on the phase structure, physical stability, and performance of spray-dried naproxen-polyvinylpyrrolidone (PVP) K 25 amorphous solid dispersions. The modulated differential scanning
Chun-Mei Zhao et al.
Environmental toxicology and chemistry, 32(4), 913-919 (2013-01-25)
The toxicity of manufactured silver nanoparticles (AgNPs) has been widely studied, but the influence of AgNPs on the major ions (such as sodium [Na] and calcium [Ca]) regulations are unknown. In the present study, a freshwater cladoceran Daphnia magna was

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