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G5882

Sigma-Aldrich

戊二醛 溶液

Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative

同義詞:

1,5-戊二醛, 五碳双缩醛 溶液

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About This Item

線性公式:
OHC(CH2)3CHO
CAS號碼:
111-30-8
分子量：:
100.12
Beilstein:
605390
MDL號碼:
MFCD00007025
分類程式碼代碼:
12352114
PubChem物質ID:
24895235
NACRES:
NA.21
暫時無法取得訂價和供貨情況

品質等級

300

種類

Grade I

形狀

liquid

濃度

25% in H2O

技術

electron microscopy: suitable (fixative)
electron microscopy: suitable

顏色

colorless

有用的pH值範圍

2.9

mp

-10 °C ((14 °F ))

溶解度

water: soluble at 20 °C

應用

cell analysis

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

InChI 密鑰

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

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相關類別

一般說明

戊二醛（1,5-戊二醛）是一种脂肪族二醛，常用作多功能生物化学试剂。戊二醛溶液由固定性能不同的单体和聚合体混合而成。其应用包括作为蛋白质交联剂，促进显微镜学、组织化学和细胞化学中酶的固定。该化合物可用作SDS-PAGE、染色或电子显微镜检查之前的胺反应性同型双功能交联剂和细胞固定剂，适用于各种形态学研究。
戊二醛可以使胺和肼衍生物与蛋白质和其它含胺聚合物高效交联。特别值得一提的是，它已被用于某些反应中，使生物素酰肼与核酸直接结合，其潜在应用为荧光酰肼和羟胺与DNA的偶联。在组织学研究中，戊二醛可用于保存组织切片，以便进行更密切的检查。

應用

戊二醛溶液已用于：
  • 固定血液样品，进行扫描电镜(SEM)观察
  • 固定支架进行SEM分析
  • 在药物实验中处理K562（白血病）细胞，永久交联细胞组分

生化／生理作用

戊二醛在生物医学研究中可用来固定细胞。还可作为健康和病理红细胞的研究工具。戊二醛广泛用于消毒各种医疗器械，包括内窥镜、透析管、血液透析比例混合和透析液供给系统、腔内探头、换能器、麻醉、呼吸治疗设备以及一次性腹腔镜塑料套管的再利用。

特點和優勢

  • 功能强大，适用于各种研究应用
  • 即用型溶液减少制备时间

其他說明

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)
为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。
如需了解生化试剂系列的更多信息，请填写此表。
推荐用于需要高纯度的技术。

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訂價

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戊二醛 溶液, 50% in H2O, suitable for photographic applications

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戊二醛 溶液, Grade I, 8% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use

G7651

戊二醛 溶液, Grade I, 50% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use

G6257

戊二醛 溶液, Grade II, 25% in H2O

G7776

戊二醛 溶液, Grade I, 70% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use

49626

戊二醛 溶液, suitable for electron microscopy, ~25% in H2O

49629

戊二醛 溶液, technical, ~50% in H2O (5.6 M)

340855

戊二醛 溶液, 50 wt. % in H2O

訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類（WGK）

WGK 3

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
0000424254
0000424254
0000391569
0000390828
0000375815

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存取文件庫

Malwina Sosnowska et al.
International journal of nanomedicine, 14, 6197-6215 (2019-09-10)
Degradation of the extracellular matrix (ECM) changes the physicochemical properties and dysregulates ECM-cell interactions, leading to several pathological conditions, such as invasive cancer. Carbon nanofilm, as a biocompatible and easy to functionalize material, could be used to mimic ECM structures
Jules D P Valentin et al.
Journal of colloid and interface science, 552, 247-257 (2019-05-28)
Many materials used in the medical settings such as catheters and contact lenses as well as most biological tissues are not purely elastic, but rather viscoelastic. While substrate elasticity has been investigated for its influence on bacterial adhesion, the impact
Mariafrancesca Cascione et al.
International journal of molecular sciences, 20(14) (2019-07-26)
The side effects induced by nanoparticle exposure at a cellular level are one of the priority research topics due to the steady increase in the use of nanoparticles (NPs). Recently, the focus on cellular morphology and mechanical behavior is gaining
Stéphane Jauréguiberry et al.
Blood, 124(2), 167-175 (2014-05-27)
Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes. These once-infected erythrocytes then return to the circulation. We analyzed hematologic
Stephanie J Bissel et al.
Journal of neuropathology and experimental neurology, 74(8), 767-777 (2015-06-27)
Human parechovirus 3 (HPeV3) is a picornavirus associated with neurologic disease in neonates. Human parechovirus 3 infection of preterm and term infants is associated with seizures and destructive periventricular white matter lesions. Despite unremarkable cerebrospinal fluid (CSF), HPeV3 RNA can
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Preparation & Staining of 3D Printed Tissues & Scaffolds

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

3D 列印組織與支架的製備與染色

生物組織的三維 (3D) 列印正迅速成為組織工程不可或缺的一部分。

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Is this concentration of 25% expressed in terms of weight by weight (w/w), weight by volume (w/v), or volume by volume (v/v)?

    1 answer

    1. The concentration of the product is 25% w/w solution.

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