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Merck
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重要文件

F8639

Supelco

泛普法宗

analytical standard

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About This Item

經驗公式(希爾表示法):
C24H31N3O
CAS號碼:
分子量::
377.52
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

形式

neat

SMILES 字串

CC(C)C1=C(CN(C)C(C)Cc2ccccc2)N(C)N(c3ccccc3)C1=O

InChI

1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3

InChI 密鑰

GNUXVOXXWGNPIV-UHFFFAOYSA-N

一般說明

Famprofazone is a pyrazole derivative and belongs to the class of non-steroidal anti-inflammatory drugs. It is widely used as an analgesic and antipyretic in medical applications.

應用

Famprofazone may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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April T Rodriguez et al.
Journal of analytical toxicology, 28(6), 432-438 (2004-11-02)
One of the 14 different drugs known to be metabolized to methamphetamine and/or amphetamine is famprofazone, a component in the multi-ingredient formulation Gewodin. Because of its conversion to methamphetamine and amphetamine, which can result in positive drug-testing results, the excretion
M Neugebauer et al.
Biomedical chromatography : BMC, 11(6), 356-361 (1997-12-31)
Famprofazone (1) metabolites were studied in human urine after medication by 50 mg oral dose. The human urine was collected over 48 h from six volunteers at time intervals of 6, 12, 24 and 48 h. The amount of famprofazone
F Musshoff et al.
International journal of legal medicine, 111(6), 305-308 (1998-11-24)
After a traffic accident a 32-year-old man was suspected of having previously taken an illegal drug. An immunochemical screening procedure revealed positive results for amphetamines in both urine and blood samples. The preliminary test was confirmed by GC/MS and both
A rapid screening LC?MS/MS method based on conventional HPLC pumps for the analysis of low molecular weight xenobiotics: application to doping control analysis
Mazzarino M, et al.
Drug Testing and Analysis, 2(7), 311-322 (2010)
H S Shin et al.
Journal of chromatography. B, Biomedical applications, 661(2), 255-261 (1994-11-18)
Detection and identification of famprofazone and its metabolite, p-hydroxydesmethylfamprofazone, were described. The identity of the new metabolite was confirmed by comparing its mass spectrum and gas chromatographic retention time with that of the synthetic standard and its derivatives. Unchanged famprofazone

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